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中华关节外科杂志(电子版) ›› 2018, Vol. 12 ›› Issue (06) : 826 -829. doi: 10.3877/cma.j.issn.1674-134X.2018.06.015

所属专题: 文献

综述

骨关节炎中软骨细胞自噬的研究进展
胡浩然1, 谢雪涛1,(), 张长青1   
  1. 1. 200233 上海交通大学附属第六人民医院骨科
  • 收稿日期:2018-01-04 出版日期:2018-12-01
  • 通信作者: 谢雪涛
  • 基金资助:
    国家自然科学基金青年项目(81401799); 上海市青年科技英才扬帆计划(14YF1412100)

Research progress of chondrocyte autophagy in osteoarthritis

Haoran Hu1, Xuetao Xie1,(), Changqing Zhang1   

  1. 1. Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China
  • Received:2018-01-04 Published:2018-12-01
  • Corresponding author: Xuetao Xie
  • About author:
    Corresponding author: Xie Xuetao, Email:
引用本文:

胡浩然, 谢雪涛, 张长青. 骨关节炎中软骨细胞自噬的研究进展[J]. 中华关节外科杂志(电子版), 2018, 12(06): 826-829.

Haoran Hu, Xuetao Xie, Changqing Zhang. Research progress of chondrocyte autophagy in osteoarthritis[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2018, 12(06): 826-829.

骨关节炎(OA)是一种临床上常见的慢性退行性疾病,是导致中老年人群行动下降和功能障碍的主要病因。自噬不仅是细胞维持代谢平衡和细胞器更新的重要机制,而且与OA的发生和发展也存在密切关系。本文就OA中软骨细胞自噬的研究进展作一综述。

Objective

Osteoarthritis (OA), a common chronic degenerative disease inclinics, is the main cause of the disability and dysfunction of middle-aged and elderly people. Autophagy is not only essential to the maintenance of metabolic balance and renewal of cellular organs, but also has close relationship with the occurrence and development of OA.This article reviewed the latest research progress of chondrocyte autophagy in OA.

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