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中华关节外科杂志(电子版) ›› 2022, Vol. 16 ›› Issue (02) : 202 -207. doi: 10.3877/cma.j.issn.1674-134X.2022.02.010

综述

软骨下骨治疗创伤性骨关节炎的研究进展
廖桃1, 曾妮1, 颜志鹏1, 李捷婷1, 倪国新2,()   
  1. 1. 350000 福州,福建医科大学附属第一医院
    2. 350000 福州,福建医科大学附属第一医院;100084 北京体育大学
  • 收稿日期:2021-08-19 出版日期:2022-04-01
  • 通信作者: 倪国新
  • 基金资助:
    国家自然科学基金(81871848)

Research progress of subchondral bone in treatment of post traumatic osteoarthritis

Tao Liao1, Ni Zeng1, Zhipeng Yan1, Jieting Li1, Guoxin Ni2,()   

  1. 1. The First Affiliated Hospital of Fujian Medical University, Fuzhou 350000, China
    2. The First Affiliated Hospital of Fujian Medical University, Fuzhou 350000, China; Beijing Sport University, Beijing 100084, China
  • Received:2021-08-19 Published:2022-04-01
  • Corresponding author: Guoxin Ni
引用本文:

廖桃, 曾妮, 颜志鹏, 李捷婷, 倪国新. 软骨下骨治疗创伤性骨关节炎的研究进展[J/OL]. 中华关节外科杂志(电子版), 2022, 16(02): 202-207.

Tao Liao, Ni Zeng, Zhipeng Yan, Jieting Li, Guoxin Ni. Research progress of subchondral bone in treatment of post traumatic osteoarthritis[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2022, 16(02): 202-207.

软骨下骨在骨关节炎的发生发展中发挥着重要的作用,也是目前研究骨关节炎发病机制及治疗的重要解剖因素。创伤性骨关节炎是骨关节炎的常见类型,通常在损伤后发展,前交叉韧带损伤是导致创伤性骨关节炎的主要原因。软骨下骨结构和功能的完整性可以反映创伤性骨关节炎的发展进程及预后。尽管长期以来软骨是骨关节炎发病机制中的研究重点,但软骨下骨在骨关节炎中的作用也越来越受关注。此外软骨下骨在创伤性骨关节炎中的病理性改变可以明确疾病的病程。在创伤性骨关节炎的治疗中,未来的研究应结合不同时期软骨下骨的改变,以软骨下骨为靶点进行防治。

Subchondral bone plays an important role in the occurrence and development of osteoarthritis, and it is also an important anatomical factor to study the pathogenesis and treatment of osteoarthritis. Post-traumatic osteoarthritis is a common type of osteoarthritis, which usually develops after injury. Anterior cruciate ligament injury is the main cause of post-traumatic osteoarthritis. The integrity of subchondral bone structure and function can reflect the development and prognosis of post-traumatic osteoarthritis. Although cartilage has been the focus of research on the pathogenesis of osteoarthritis for a long time, the role of subchondral bone in osteoarthritis has attracted more and more attention. In addition, the pathological changes of subchondral bone in post-traumatic osteoarthritis can clarify the course of the disease. In the treatment of post-traumatic osteoarthritis, future research should combine the changes of subchondral bone in different periods and take subchondral bone as the target for prevention and treatment.

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