切换至 "中华医学电子期刊资源库"
高级检索
中华关节外科杂志(电子版)

中华关节外科杂志(电子版) ›› 2023, Vol. 17 ›› Issue (03) : 415 -423. doi: 10.3877/cma.j.issn.1674-134X.2023.03.018

综述

前交叉韧带损伤及重建后继发性膝骨关节炎的研究进展
赵宇, 赵松, 赵金忠†()   
  1. 215163　苏州，南京大学医学院附属苏州医院骨科
    200233　上海交通大学附属第六人民医院运动医学科
  • 收稿日期:2022-02-12 出版日期:2023-06-01
  • 通信作者: 赵金忠
  • 基金资助:
    国家重点研发计划项目(2018YFC1106200); 上海市浦江人才计划(2020PJD041); 苏州高新区青年科技项目(2019Q014)

Research progress in secondary knee osteoarthritis after anterior cruciate ligament injury and reconstruction

Yu Zhao, Song Zhao, Jinzhong Zhao†()   

  1. Department of Orthopedics, the Affiliated Suzhou Hospital of Medical School, Nanjing University, Suzhou 215163, China
    Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China
  • Received:2022-02-12 Published:2023-06-01
  • Corresponding author: Jinzhong Zhao
全文 ( ) 下载PDF ( ) 导出引用
引用本文：

赵宇, 赵松, 赵金忠. 前交叉韧带损伤及重建后继发性膝骨关节炎的研究进展[J/OL]. 中华关节外科杂志(电子版), 2023, 17(03): 415-423.

Yu Zhao, Song Zhao, Jinzhong Zhao. Research progress in secondary knee osteoarthritis after anterior cruciate ligament injury and reconstruction[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(03): 415-423.

前交叉韧带(ACL)断裂是常见的膝关节运动损伤，篮球、足球等接触性运动的运动员ACL损伤的年发病率为0.15%~3.7%，其损伤后对膝关节的稳定性影响巨大。对于ACL损伤的治疗方案仍存在争议，目前主要的治疗方式为手术治疗和保守治疗，虽然手术重建韧带可以部分恢复膝关节的稳定性，但从长期随访结果来看，ACL重建手术未能有效降低膝关节创伤后骨关节炎(PTOA)的发病率。本文旨在通过文献检索，对膝关节PTOA的发病机制、保守治疗与手术治疗，以及不同手术方式(单束、双束及前外侧结构重建等)对膝关节PTOA的影响进行综述，以期针对ACL损伤后的治疗为临床医生提供参考，尽可能降低ACL损伤后骨关节炎的发生率。

关键词: 膝关节, 前交叉韧带重建, 创伤和损伤

Anterior cruciate ligament(ACL) rupture is a common sports injury of the knee joint. The incidence rate of ACL injuries in basketball, football and other contact sports athletes is 0.15% to 3.7%, which has a great influence on the stability of the knee joint after injury. The treatment plan for anterior cruciate ligament injury is still controversial. The main treatment is surgical treatment and conservative treatment. Although reconstruction of ligament can partially restore the stability of the knee joint, but from the long-term follow-up results, ACL reconstruction surgery can’t effectively reduce the incidence rate of post-traumatic osteoarthritis (PTOA) of the knee. Through literature search, this paper aimed to explore the pathogenesis, conservative treatment and surgical treatment of knee PTOA, and the effects of different surgical methods (single bundle, double bundle and anterolateral structural reconstruction) on knee PTOA, in order to provide reference for clinicians on the treatment after ACL injury and reduce the incidence of osteoarthritis after ACL injury as much as possible.

Key words: Knee joint, Anterior cruciate ligament reconstruction, Wounds and injuries
图1 ACL(前交叉韧带)损伤后PTOA(创伤后骨关节炎)可能的发病机制注：↑－增加；↓－减少
Figure 1 The pathogenesis of post-traumatic osteoarthritis following ACL injuries
[1]
Wang LJ, Zeng N, Yan ZP, et al. Post-traumatic osteoarthritis following ACL injury[J/OL]. Arthritis Res Ther, 2020, 22(1): 57. DOI: 10.1186/s13075-020-02156-5.
[2]
Riccardo C, Fabio C, Pietro R. Knee osteoarthritis after reconstruction of isolated anterior cruciate ligament injuries: asystematic literature review[J]. Joints, 2017, 5(1): 39－43.
[3]
Everhart JS, Yalcin S, Spindler KP. Twenty-year outcomes after anterior cruciate ligament reconstruction: asystematic review of prospectively collected data[J]. Am J Sports Med, 2022, 50(10): 2842－2852.
[4]
Diemer F, Zebisch J, Saueressig T. Consequences of anterior cruciate ligament rupture: a systematic umbrella review[J]. Sportverletz Sportschaden, 2022, 36(1): 18－37.
[5]
Cuzzolin M, Previtali D, Zaffagnini S, et al. Anterior cruciate ligament reconstruction versus nonoperative treatment: better function and less secondary meniscectomies but No difference in knee osteoarthritis-ameta-analysis[J]. Cartilage, 2021, 13(1_suppl): 1658S－1670S.
[6]
Narez GE, Fischenich KM, Donahue TLH. Experimental animal models of post-traumatic osteoarthritis of the knee[J/OL]. Orthop Rev, 2020, 12(2): 8448. DOI: 10.4081/or.2020.8448.
[7]
Zhao R, Dong Z, Wei X, et al. Inflammatory factors are crucial for the pathogenesis of post-traumatic osteoarthritis confirmed by a novel porcine model: " Idealized" anterior cruciate ligament reconstruction" and gait analysis[J/OL]. Int Immunopharmacol, 2021, 99: 107905. DOI: 10.1016/j.intimp.2021.107905.
[8]
Carbone A, Rodeo S. Review of current understanding of post-traumatic osteoarthritis resulting from sports injuries[J]. J Orthop Res, 2017, 35(3): 397－405.
[9]
Ding L, Buckwalter JA, Martin JA. DAMPs synergize with cytokines or fibronectin fragment on inducing chondrolysis but lose effect when acting alone[J/OL]. Mediators Inflamm, 2017, 2017: 2642549. DOI: 10.1155/2017/2642549.
[10]
Riegger J, Brenner RE. Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis[J/OL]. Cell Death Dis, 2019, 10(10): 683. DOI: 10.1038/s41419-019-1930-5.
[11]
Iqbal SM, Leonard C, Regmi SC, et al. Lubricin/proteoglycan 4 binds to and regulates the activity of toll-like receptors in vitro[J]. Sci Rep, 2016, 6: 18910. DOI: 10.1038/srep18910.
[12]
Rosenberg JH, Rai V, Dilisio MF, et al. Damage-associated molecular patterns in the pathogenesis of osteoarthritis: potentially novel therapeutic targets[J]. Mol Cell Biochem, 2017, 434(1－2): 171－179.
[13]
Brown SB, Hornyak JA, Jungels RR, et al. Characterization of post-traumatic osteoarthritis in rats following anterior cruciate ligament rupture by non-invasive knee injury (NIKI)[J]. J Orthop Res, 2020, 38(2): 356－367.
[14]
McCulloch K, Huesa C, Dunning L, et al. Accelerated post traumatic osteoarthritis in a dual injury murine model[J]. Osteoarthritis Cartilage, 2019, 27(12): 1800－1810.
[15]
Alonso B, Bravo B, Mediavilla L, et al. Osteoarthritis-related biomarkers profile in chronic anterior cruciate ligament injured knee[J]. Knee, 2020, 27(1): 51－60.
[16]
Riegger J, Brenner RE. Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment[J/OL]. Int J Mol Sci, 2020, 21(5): 1560. DOI: 10.3390/ijms21051560.
[17]
Huang K, Cai HL, Zhang PL, et al. Comparison between two rabbit models of posttraumatic osteoarthritis: a longitudinal tear in the medial meniscus and anterior cruciate ligament transection[J]. J Orthop Res, 2020, 38(12): 2721－2730.
[18]
Favero M, Belluzzi E, Trisolino G, et al. Inflammatory molecules produced by meniscus and synovium in early and end-stage osteoarthritis: a coculture study[J]. J Cell Physiol, 2019, 234(7): 11176－11187.
[19]
Proffen BL, Sieker JT, Murray MM, et al. Extracellular matrix-blood composite injection reduces post-traumatic osteoarthritis after anterior cruciate ligament injury in the rat[J]. J Orthop Res, 2016, 34(6): 995－1003.
[20]
Titchenal MR, Chu CR, Erhart-Hledik JC, et al. Early changes in knee center of rotation during walking after anterior cruciate ligament reconstruction correlate with later changes in patient-reported outcomes[J]. Am J Sports Med, 2017, 45(4): 915－921.
[21]
Øiestad BE, Juhl CB, Culvenor AG, et al. Knee extensor muscle weakness is a risk factor for the development of knee osteoarthritis: an updated systematic review and meta-analysis including 46 819 men and women[J]. Br J Sports Med, 2022, 56(6): 349－355.
[22]
Harkey MS, Luc-Harkey BA, Lepley AS, et al. Persistent muscle inhibition after anterior cruciate ligament reconstruction: role of reflex excitability[J]. Med Sci SportsExerc, 2016, 48(12): 2370－2377.
[23]
Smeets A, Malfait B, Dingenen B, et al. Is knee neuromuscular activity related to anterior cruciate ligament injury risk? A pilot study[J]. Knee, 2019, 26(1): 40－51.
[24]
Tayfur B, Charuphongsa C, Morrissey D, et al. Neuromuscular function of the knee joint following knee injuries: does it ever get back to normal? A systematic review with meta-analyses[J]. Sports Med, 2021, 51(2): 321－338.
[25]
Harris KP, Driban JB, Sitler MR, et al. Tibiofemoral osteoarthritis after surgical or nonsurgical treatment of anterior cruciate ligament rupture: asystematic review[J]. J Athl Train, 2017, 52(6): 507－517.
[26]
He C, He W, Li Y, et al. Biomechanics of knee joints after anterior cruciate ligament reconstruction[J]. J Knee Surg, 2018, 31(4): 352－358.
[27]
Wellsandt E, Khandha A, Capin J, et al. Operative and nonoperative management of anterior cruciate ligament injury: differences in gait biomechanics at 5 years[J]. J Orthop Res, 2020, 38(12): 2675－2684.
[28]
Hagmeijer MH, Hevesi M, Desai VS, et al. Secondary meniscal tears in patients with anterior cruciate ligament injury: relationship among operative management, osteoarthritis, and arthroplasty at 18-year mean follow-up[J]. Am J Sports Med, 2019, 47(7): 1583－1590.
[29]
Webster KE, Hewett TE. Anterior cruciate ligament injury and knee osteoarthritis: an umbrella systematic review and meta-analysis[J]. Clin J Sport Med, 2022, 32(2): 145－152.
[30]
Ding DY, Tucker LY, RuggCM. Comparison of anterior cruciate ligament tears treated nonoperatively versus with reconstruction: risk of subsequent surgery[J]. Am J Sports Med, 2022, 50(3): 652－661.
[31]
Konrads C, Reppenhagen S, Belder D, et al. Long-term outcome of anterior cruciate ligament tear without reconstruction: a longitudinal prospective study[J]. Int Orthop, 2016, 40(11): 2325－2330.
[32]
Krause M, Freudenthaler F, Frosch KH, et al. Operative versus conservative treatment of anterior cruciate ligament rupture[J]. Dtsch Arztebl Int, 2018, 115(51－52): 855－862.
[33]
Lee YS, Lee OS, Lee SH, et al. Effect of the timing of anterior cruciate ligament reconstruction on clinical and stability outcomes: ASystematicreview and meta-analysis[J]. Arthroscopy, 2018, 34(2): 592－602.
[34]
Ferguson D, Palmer A, Khan S, et al. Early or delayed anterior cruciate ligament reconstruction: is one superior? A systematic review and meta-analysis[J]. Eur J Orthop Surg Traumatol, 2019, 29(6): 1277－1289.
[35]
Krutsch W, Zellner J, Baumann F, et al. Timing of anterior cruciate ligament reconstruction within the first year after trauma and its influence on treatment of cartilage and meniscus pathology[J]. Knee Surg Sports Traumatol Arthrosc, 2017, 25(2): 418－425.
[36]
Herbst E, Hoser C, Gföller P, et al. Impact of surgical timing on the outcome of anterior cruciate ligament reconstruction[J]. Knee Surg SportsTraumatolArthrosc, 2017, 25(2): 569－577.
[37]
Hur CI, Song EK, Kim SK, et al. Early anterior cruciate ligament reconstruction can save meniscus without any complications[J]. Indian J Orthop, 2017, 51(2): 168－173.
[38]
Manandhar RR, Chandrashekhar K, Kumaraswamy V, et al. Functional outcome of an early anterior cruciate ligament reconstruction in comparison to delayed: are we waiting in vain？[J]. J Clin Orthop Trauma, 2018, 9(2): 163－166.
[39]
Tardy N, Boisrenoult P, Teissier P, et al. Clinical outcomes after multiligament injured knees: medial versus lateral reconstructions[J]. Knee Surg SportsTraumatolArthrosc, 2017, 25(2): 524－531.
[40]
Chen KH, Chiang ER, Wang HY, et al. Correlation of meniscal tear with timing of anterior cruciate ligament reconstruction in patients without initially concurrent meniscal tear[J]. J Knee Surg, 2019, 32(11): 1128－1132.
[41]
Kim SH, Han SJ, Park YB, et al. A systematic review comparing the results of early vs delayed ligament surgeries in single anterior cruciate ligament and multiligament knee injuries[J/OL]. Knee Surg Relat Res, 2021, 33(1): 1. DOI: 10.1186/s43019-020-00086-9.
[42]
Wirth W, Eckstein F, Culvenor AG, et al. Early anterior cruciate ligament reconstruction does not affect 5 year change in knee cartilage thickness: secondary analysis of a randomized clinical trial[J]. Osteoarthritis Cartilage, 2021, 29(4): 518－526.
[43]
Matthewson G, Kooner S, Rabbani R, etal. Does a delay in anterior cruciate ligament reconstruction increase the incidence of secondary pathology in the knee? A systematic review and meta-analysis[J]. Clin J Sport Med, 2021, 31(3): 313－320.
[44]
Heard BJ, Barton KI, Chung M, et al. Single intra-articular dexamethasone injection immediately post-surgery in a rabbit model mitigates early inflammatory responses and post-traumatic osteoarthritis-like alterations[J]. J Orthop Res, 2015, 33(12): 1826－1834.
[45]
Chen H, Tie K, Qi Y, et al. Anteromedial versus transtibial technique in single-bundle autologous hamstring ACL reconstruction: a meta-analysis of prospective randomized controlled trials[J/OL]. J Orthop Surg Res, 2017, 12(1): 167. DOI: 10.1186/s13018-017-0671-3.
[46]
Rothrauff BB, Jorge A, de Sa D, et al. Anatomic ACL reconstruction reduces risk of post-traumatic osteoarthritis: a systematic review with minimum 10-year follow-up[J]. Knee Surg SportsTraumatolArthrosc, 2020, 28(4): 1072－1084.
[47]
Oh JY, Kim KT, Park YJ, et al. Biomechanical comparison of single-bundle versus double-bundle anterior cruciate ligament reconstruction: a meta-analysis[J/OL]. Knee Surg Relat Res, 2020, 32(1): 14. DOI: 10.1186/s43019-020-00033-8.
[48]
Malempati CS, Metzler AV, Johnson DL. Single-bundle anatomic anterior cruciate ligament reconstruction: surgical technique pearls and pitfalls[J]. Clin Sports Med, 2017, 36(1): 53－70.
[49]
Wang W, Shen L, Jin Z, et al. Clinical efficacy of anterior cruciate ligament reconstruction: is an anatomical double-bundle or anatomical single-bundle better? A meta-analysis [J]. Int J Clin Exp Med，2018，11(11): 11357－11371.
[50]
Chen K, Zhu W, Zheng Y, et al. A retrospective study to compare the clinical effects of individualized anatomic single-and double-bundle anterior cruciate ligament reconstruction surgery[J/OL]. Sci Rep, 2020, 10(1): 14712. DOI: 10.1038/s41598-020-71721-4.
[51]
Maeyama A, Hoshino Y, Kato Y, et al. Anatomic double bundle ACL reconstruction outperforms any types of single bundle ACL reconstructions in controlling dynamic rotational laxity[J]. Knee Surg SportsTraumatolArthrosc, 2018, 26(5): 1414－1419.
[52]
Mao Z, Wang J, Wang Y, et al. Double-bundle anterior cruciate ligament reconstruction technique has advantages in chondroprotection and knee laxity control compared with single-bundle technique: a long-term follow-up with a minimum of 12 years[J]. Knee Surg Sports Traumatol Arthrosc, 2021, 29(9): 3105－3114.
[53]
Mayr HO, Stoehr A. Editorial commentary: No difference in knee osteoarthritis after single-bundle versus double-bundle anterior cruciate ligament reconstruction[J]. Arthroscopy, 2019, 35(3): 1004－1005.
[54]
Järvelä S, Kiekara T, Suomalainen P, et al. Double-bundle versus single-bundle anterior cruciate ligament reconstruction：aprospective randomized study with 10-year results[J]. Am J Sports Med, 2017, 45(11): 2578－2585.
[55]
Chen H, Chen B, Tie K, et al. Single-bundle versus double-bundle autologous anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials at 5-year minimum follow-up[J/OL]. J Orthop Surg Res, 2018, 13(1): 50. DOI: 10.1186/s13018-018-0753-x.
[56]
Yoon KH, Kim JS, Kim SJ, et al. Eight-year results of transtibial nonanatomic single-bundle versus double-bundle anterior cruciate ligament reconstruction: clinical, radiologic outcomes and survivorship[J/OL]. J Orthop Surg, 2019, 27(2): 2309499019840827. DOI: 10.1177/2309499019840827.
[57]
中国研究型医院学会运动医学专业委员会. 膝关节前外侧结构加强及重建专家共识(2021年版)[J/CD]. 中华关节外科杂志(电子版), 2021, 15(2): 131－136.
[58]
Getgood A, Brown C, Lording T, et al. The anterolateral complex of the knee: results from the International ALC Consensus Group Meeting[J]. Knee Surg Sports Traumatol Arthrosc, 2019, 27(1): 166－176.
[59]
Helito CP, Sobrado MF, Giglio PN, et al. Combined reconstruction of the anterolateral ligament in patients with anterior cruciate ligament injury and ligamentous hyperlaxity leads to better clinical stability and a lower failure rate than isolated anterior cruciate ligament reconstruction[J]. Arthroscopy, 2019, 35(9): 2648－2654.
[60]
Inderhaug E, Stephen JM, Williams A, et al. Anterolateral tenodesis or anterolateral ligament complex reconstruction：effect of flexion angle at graft fixation when combined with ACL reconstruction[J]. Am J Sports Med, 2017, 45(13): 3089－3097.
[61]
Geeslin AG, Moatshe G, Chahla J, et al. Anterolateral knee extra-articular stabilizers：arobotic study comparing anterolateral ligament reconstruction and modified lemaire lateral extra-articular tenodesis[J]. Am J Sports Med, 2018, 46(3): 607－616.
[62]
Inderhaug E, Stephen JM, Williams A, et al. Biomechanical comparison of anterolateral procedures combined with anterior cruciate ligament reconstruction[J]. Am J Sports Med, 2017, 45(2): 347－354.
[63]
Zaffagnini S, Marcheggiani Muccioli GM, Grassi A, et al. Over-the-top ACL reconstruction plus extra-articular lateral tenodesis with hamstring tendon grafts: prospective evaluation with 20-year minimum follow-up[J]. Am J Sports Med, 2017, 45(14): 3233－3242.
[64]
Mao Y, Zhang K, Li J, et al. Supplementary lateral extra-articular tenodesis for residual anterolateral rotatory instability in patients undergoing single-bundle anterior cruciate ligament reconstruction: ameta-analysis of randomized controlled trials[J/OL]. Orthop J Sports Med, 2021, 9(5): 23259671211002282. DOI: 10.1177/23259671211002282.
[65]
Chen J, Wang C, Xu C, et al. Effects of anterolateral structure augmentation on the in vivokinematics of anterior cruciate ligament-reconstructed knees[J]. Am J Sports Med, 2021, 49(3): 656－666.
[66]
Castoldi M, Magnussen RA, Gunst S, et al. A randomized controlled trial of bone-patellar tendon-bone anterior cruciate ligament reconstruction with and without lateral extra-articular tenodesis: 19-year clinical and radiological follow-up[J]. Am J Sports Med, 2020, 48(7): 1665－1672.
[67]
Saithna A, Daggett M, Helito CP, et al. Clinical results of combined ACL and anterolateral ligament reconstruction: anarrative review from the SANTI study group[J]. J Knee Surg, 2021, 34(9): 962－970.
[68]
Fan D, Ma J, Zhang L. Patellar tendon versus artificial grafts in anterior cruciate ligament reconstruction: a systematic review and meta-analysis[J/OL]. J Orthop Surg Res, 2021, 16(1): 478. DOI: 10.1186/s13018-021-02624-x.
[69]
Arnold MP, Calcei JG, Vogel N, et al. ACL Study Group survey reveals the evolution of anterior cruciate ligament reconstruction graft choice over the past three decades[J]. Knee Surg SportsTraumatolArthrosc, 2021, 29(11): 3871－3876.
[70]
Duchman KR, Lynch TS, Spindler KP. Graft selection in anterior cruciate ligament surgery: who gets what and why？[J]. Clin Sports Med, 2017, 36(1): 25－33.
[71]
Lecoq FA, Parienti JJ, Murison J, et al. Graft choice and the incidence of osteoarthritis after anterior cruciate ligament reconstruction: acausal analysis from a cohort of 541 patients[J]. Am J Sports Med, 2018, 46(12): 2842－2850.
[72]
Ciccotti MC, Secrist E, Tjoumakaris F, et al. Anatomic anterior cruciate ligament reconstruction via independent tunnel drilling: asystematic review of randomized controlled trials comparing patellar tendon and hamstring autografts[J]. Arthroscopy, 2017, 33(5): 1062－1071.e5.
[73]
Johnston CD, Goodwin JS, Spang JT, et al. Gait biomechanics in individuals with patellar tendon and hamstring tendon anterior cruciate ligament reconstruction grafts[J]. J Biomech, 2019, 82: 103－108.
[74]
Zhao L, Lu M, Deng M, et al. Outcome of bone-patellar tendon-bone vs hamstring tendon autograft for anterior cruciate ligament reconstruction：a meta-analysis of randomized controlled trials with a 5-year minimum follow-up[J/OL]. Medicine, 2020, 99(48): e23476. DOI: 10.1097/MD.0000000000023476.
[75]
Macri EM, Stefanik JJ, Khan KK, et al. Is tibiofemoral or patellofemoral alignment or trochlear morphology associated with patellofemoral osteoarthritis? A systematic review[J]. Arthritis Care Res, 2016, 68(10): 1453－1470.
[76]
Macri EM, Culvenor AG, Morris HG, et al. Lateral displacement, sulcus angle and trochlear angle are associated with early patellofemoral osteoarthritis following anterior cruciate ligament reconstruction[J]. Knee Surg SportsTraumatolArthrosc, 2018, 26(9): 2622－2629.
[77]
Culvenor AG, Perraton L, Guermazi A, et al. Knee kinematics and kinetics are associated with early patellofemoral osteoarthritis following anterior cruciate ligament reconstruction[J]. Osteoarthritis Cartilage, 2016, 24(9): 1548－1553.
[78]
Macri EM, Patterson BE, Crossley KM, et al. Does patellar alignment or trochlear morphology predict worsening of patellofemoral disease within the first 5 years after anterior cruciate ligament reconstruction？[J]. Eur J Radiol, 2019, 113: 32－38.
[79]
Rai MF, Brophy RH, Sandell LJ. Osteoarthritis following meniscus and ligament injury: insights from translational studies and animal models[J]. Curr Opin Rheumatol, 2019, 31(1): 70－79.
[80]
Rai MF, Brophy RH, Rosen V. Molecular biology of meniscus pathology: lessons learned from translational studies and mouse models[J]. J Orthop Res, 2020, 38(9): 1895－1904.
[81]
Brophy RH, Sandell LJ, Rai MF. Traumatic and degenerative Meniscustears have different gene expression signatures[J]. Am J Sports Med, 2017, 45(1): 114－120.
[82]
Kamatsuki Y, Furumatsu T, Fujii M, et al. Complete tear of the lateral meniscus posterior root is associated with meniscal extrusion in anterior cruciate ligament deficient knees[J]. J Orthop Res, 2018, 36(7): 1894－1900.
[83]
Poulsen E, Goncalves GH, Bricca A, et al. Knee osteoarthritis risk is increased 4-6 fold after knee injury-a systematic review and meta-analysis[J]. Br J Sports Med, 2019, 53(23): 1454－1463.
[84]
Cristiani R, Rönnblad E, Engström B, et al. Medial Meniscusresection increases and medial Meniscusrepair preserves anterior knee laxity：acohort study of 4497 patients with primary anterior cruciate ligament reconstruction[J]. Am J Sports Med, 2018, 46(2): 357－362.
[85]
Cheung EC, DiLallo M, Feeley BT, et al. Osteoarthritis and ACL reconstruction-myths and risks[J]. Curr Rev Musculoskelet Med, 2020, 13(1): 115－122.
[86]
Chang JC, Sebastian A, Murugesh DK, et al. Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis[J]. J Orthop Res, 2017, 35(3): 474－485.
[87]
Fischenich KM, Pauly HM, Button KD, et al. A study of acute and chronic tissue changes in surgical and traumatically-induced experimental models of knee joint injury using magnetic resonance imaging and micro-computed tomography[J]. Osteoarthritis Cartilage, 2017, 25(4): 561－569.
[1] 苏介茂, 齐岩松, 王永祥, 魏宝刚, 马秉贤, 张鹏飞, 魏兴华, 徐永胜. 关节镜手术在早中期膝骨关节炎治疗的应用进展[J/OL]. 中华关节外科杂志(电子版), 2024, 18(05): 646-652.
[2] 杨滢甄, 黄子荣, 梁家敏, 黄晓芳, 胡艳, 朱伟民. 膝关节前交叉韧带重建术前康复治疗的研究进展[J/OL]. 中华关节外科杂志(电子版), 2024, 18(04): 538-544.
[3] 赵飞鸿, 陈颖杰, 林静芳, 郑晓春, 廖燕凌. 超声引导下周围神经阻滞对髋膝关节置换术后恢复的影响[J/OL]. 中华关节外科杂志(电子版), 2024, 18(04): 457-468.
[4] 高小康, 张净宇, 刘金伟, 田东牧, 胡永成, 徐卫国. 连接型人工膝关节假体运动和负重模式的演变和进展[J/OL]. 中华关节外科杂志(电子版), 2024, 18(04): 505-516.
[5] 陆帅, 徐亮, 张尧, 方超, 赵其纯. 前交叉韧带重建术半月板成形对膝骨关节炎的远期影响[J/OL]. 中华关节外科杂志(电子版), 2024, 18(02): 167-174.
[6] 蔡雨琦, 史尉利, 陶立元, 曹建夫, 崔国庆, 杨渝平. 支持带松解联合外侧成形治疗髌骨外侧过度挤压综合征[J/OL]. 中华关节外科杂志(电子版), 2024, 18(02): 186-192.
[7] 韩伟峰, 王典, 陈艺丹, 曾峥. 关节镜下半月板成形术与康复训练治疗中年退行性内侧半月板撕裂的疗效比较[J/OL]. 中华损伤与修复杂志(电子版), 2024, 19(02): 134-140.
[8] 高瑞, 康迪斯, 秦蘅, 胡月明, 初同伟, 代丽. 加速康复管理改善膝关节置换术后肺部感染并发症和疗效的Meta分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(02): 234-237.
[9] 宋庆成, 郑占乐, 王天瑞, 王宇钏, 张凯旋, 纳静, 蔚佳昊, 杨思繁, 宋九宏, 张英泽. “人老膝不老”：膝关节健康管理的全方位探索与实践[J/OL]. 中华老年骨科与康复电子杂志, 2024, 10(06): 321-324.
[10] 郑占乐, 王宇钏, 蔚佳昊, 宋庆成, 张凯旋, 纳静, 王天瑞, 宋九宏, 张英泽, 王娟. 保膝须“开膝”——“开膝”在膝骨关节炎中的临床应用价值[J/OL]. 中华老年骨科与康复电子杂志, 2024, 10(06): 325-330.
[11] 王浩汀, 尚运涛, 曹光, 张延祠, 李军勇. 胫骨高位截骨联合关节镜与单髁置换治疗单间室膝关节骨性关节炎的临床疗效比较[J/OL]. 中华老年骨科与康复电子杂志, 2024, 10(04): 229-236.
[12] 于晓光, 秦永辉, 李佳, 贾国兴, 李军, 赵振栓, 刘国彬. 人工单髁置换术治疗膝关节内侧间室骨关节炎合并前交叉韧带功能不良的近期疗效[J/OL]. 中华临床医师杂志(电子版), 2024, 18(04): 337-342.
[13] 临床多学科协作专家组. 腹盆部创伤急诊CT 专家推荐指南（2024）[J/OL]. 中华诊断学电子杂志, 2024, 12(04): 222-229.
[14] 田峰瑞, 蒋锦源, 李阳, 张连阳. Morel-Lavallée 损伤继发血清肿一例[J/OL]. 中华诊断学电子杂志, 2024, 12(04): 245-248.
[15] 陈念, 张连阳. 严重创伤救治中全血输注进展[J/OL]. 中华诊断学电子杂志, 2024, 12(03): 145-148.
阅读次数
全文


摘要

版权所有 中华医学会 中华医学电子音像出版社有限责任公司  京ICP备14006079号-1  网络出版服务许可证：(署)网出证(京)字第075号