Research progress of clinical preparation methods of platelet-rich plasma in China

doi:10.3877/cma.j.issn.1674-134X.2020.02.011

Abstract

Abstract:

Autologous platelet-rich plasma (PRP) is platelet concentrate separated from autologous blood by centrifugation. In the past two decades, it has been widely used in various medical fields such as orthopedics, oral and maxillofacial surgery, plastic and cosmetic surgery. However, up to now, the consistent standard for PRP clinical preparation hasn’t established. Different preparation methods may lead to different components and clinical effects of PRP, which brings many problems for clinical practitioners to apply PRP. According the literatures (Chinese and English) on PRP preparation published in China, the parameters of domestic PRP preparation methods, including blood collection, centrifugation equipment, number of centrifugation, centrifugal force, centrifugation time and volume of PRP, are quite different. Other indicators of PRP, such as leukocyte concentration, platelet enrichment factor and recovery rate, are also unstable and most are not reptorted. Therefore, there is an urgent need for high-quality research or guidelines to standardize and guide the preparation of clinical PRP.

Key words: Platelet-rich plasma, Clinical study, Methods, Centrifugation

Yuxuan Wei, Zhaoyuan Zhang, Zhengying Fan, Ting Yuan. Research progress of clinical preparation methods of platelet-rich plasma in China[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2020, 14(02): 196-200.

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