Research progress of non-coding RNA in osteoarthritis

doi:10.3877/cma.j.issn.1674-134X.2020.02.010

Abstract

Abstract:

Osteoarthritis (OA) is a common articular degenerative disease, which has become one of the major diseases that can cause the disability of the elderly in the world, and seriously affected the life quality of patients. In recent years, the studies on osteoarthritis have shown that non-coding RNA plays an important role in the development of osteoarthritis.And the studies on non-coding RNA may provide certain theoretical basis for the early diagnosis and clinical transformation of treatment of osteoarthritis. This paper reviewed the classification, mechanism and function based on current research status of non-coding RNA (ncRNAs) , and prospected its development in the future.

Key words: Osteoarthritis, RNA, untranslated, Cartilage

Xingzhao Wen, Zhiqi Zhang. Research progress of non-coding RNA in osteoarthritis[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2020, 14(02): 189-195.

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