研究全膝关节置换治疗骨关节炎的近中期手术效果，探讨手术方法与术后效果。

回顾性分析了皖南医学院弋矶山医院2010年7年至2018年3月临床资料。膝关节骨关节炎手术患者共81例，平均疼痛时间(8±3)年，均采用后稳定型假体，膝关节内外翻、屈曲畸形通过术中骨赘清理、内外侧副韧带和后方关节囊等软组织松解等技术矫正。术后关节囊内注入氨甲环酸抗凝及早期进行康复治疗。术前及术后拍摄下肢全长X片及膝关节正侧位X片记录股胫角度和屈曲畸形角度，统计手术时间、术后引流量。术后随访1、3、6、12、24月复查膝关节正侧位X线，记录膝关节活动度和疼痛情况，并进行膝关节协会评分(KSS)。用SPSS 17.0软件，数据采用配对t检验分析。

平均随访时间(22±5)个月，手术时间平均(71±6)min，引流量平均(380±5)ml，膝关节股胫角术后平均为(1.3±1.0)°，术后有4例术后出现膝前痛。无血管及神经损伤等并发症，下肢力线基本恢复正常。无术后感染发生。随访复查膝关节正侧位X线片，未发现假体松动、下沉。随访膝关节活动度、疼痛。膝关节KSS评分有显著改善(临床t＝－66，功能t＝－91.7，P<0.05) 。

全膝关节置换术治疗膝关节骨关节炎，术中应用骨赘清理、内外侧，后方关节囊等软组织松解等手术技术，可纠正内外翻畸形，恢复下肢力线、改善膝关节活动度和缓解疼痛，临床效果满意。

To estimate the short and mid-term effects of total knee arthroplasty(TKA) as well as to explore the surgical skills and postoperative effects.

A retrospective analysis was performed on the clinical data of 81 patients who received TKA between July 2010 and March 2018 in Yi-Ji-Shan Hospital of Wannan Medical College. The duration of disease ranged from one to 25 years, mean (8±3) years. Posterior stabilizing (PS) prosthesis was used for all the cases. After removal of osteophytes and osteotomy, selected soft tissue release was carried out to correct knee deformity. Post operative tranexamic acid was injected into articular cavity. Rehabilitative exercises were performed in early stage. X-ray pictures of full-length lower limb and knee were recorded pre- and post-operatively. The flexion and extend angles, internal and external varus angles were recorded. The operation time and drainage volumes were also recorded. Post-operative follow-up was performed in one, three, six, 12 and 24 months. The results were evaluated according to Knee Society score (KSS).

The mean duration of follow-up was (22±5) months. The operation time was (71±6) min on average, the mean volume of drainage was (380±5) ml, mean tibiofemoral angle of knee was corrected to (1.3±1.0)° post-operation. Anterior pain occurred in four patients. No neurovascular injury was found, and force line of lower limb was corrected to normal. The X-ray films showed no evidence of obvious radiolucent line, osteolysis, prosthesis subsidence or limb alignment change. KSS of the last followed-up was significantly better than the preoperative score, which was significantly different (clinic t =-66, function t =-91.7, P<0.05).

By removing the osteophytes and selected soft tissue releasing, TKA can correct the deformity of knee osteoarthritis, and restore the force line of lower limb, improve range of motion and function of knee; the clinical effect is satisfactory.