切换至 "中华医学电子期刊资源库"

中华关节外科杂志(电子版) ›› 2018, Vol. 12 ›› Issue (01) : 77 -86. doi: 10.3877/cma.j.issn.1674-134X.2018.01.014

所属专题: 文献

荟萃研究

收肌管阻滞与股神经阻滞在全膝关节置换术后镇痛疗效的Meta分析
李灿锋1, 曾羿1, 沈彬1,(), 裴福兴1, 杨静1, 周宗科1, 康鹏德1   
  1. 1. 610041 成都,四川大学华西医院骨科
  • 收稿日期:2016-10-16 出版日期:2018-02-01
  • 通信作者: 沈彬
  • 基金资助:
    卫生行业科研专项项目(201302007); 四川省科技厅科技支撑计划(2014SZ0023-2)

Effects of adductor canal block and femoral nerve block for postoperative analgesis after total knee arthroplasty

Canfeng Li1, Yi Zeng1, Bin Shen1,(), Fuxing Pei1, Jing Yamg1, Zongke Zhou1, Pengde Kang1   

  1. 1. Department of orthopedics, West China Hospital of Sichuan University, Chengdu 610041, China
  • Received:2016-10-16 Published:2018-02-01
  • Corresponding author: Bin Shen
  • About author:
    Corresponding author: Shen Bin, Email:
引用本文:

李灿锋, 曾羿, 沈彬, 裴福兴, 杨静, 周宗科, 康鹏德. 收肌管阻滞与股神经阻滞在全膝关节置换术后镇痛疗效的Meta分析[J/OL]. 中华关节外科杂志(电子版), 2018, 12(01): 77-86.

Canfeng Li, Yi Zeng, Bin Shen, Fuxing Pei, Jing Yamg, Zongke Zhou, Pengde Kang. Effects of adductor canal block and femoral nerve block for postoperative analgesis after total knee arthroplasty[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2018, 12(01): 77-86.

目的

系统评价收肌管阻滞(ACB)与股神经阻滞(FNB)在全膝关节置换(TKA)术后镇痛及早期康复中临床疗效差异,为临床提供参考。

方法

检索Cochrane图书馆、PubMed、EMbase、CNKI、维普资讯数据库及万方数据库等中英文数据库,检索截止日期为2016年8月。由两名评价员独立筛查文献、提取资料和方法学质量评估,采用Rev Man 5.2.0软件进行Meta分析,并绘制漏斗图评定有无发表偏倚。

结果

一共纳入12篇临床随机对照试验文献(9篇英文文献,3篇中文文献),共分析772膝,其中ACB组382膝,FNB组390膝。Meta分析结果显示:ACB组与FNB组患者视觉模拟(VAS)疼痛评分分别在术后2~4 h、6~8 h、24 h及48 h的静息评分[WMD=0.20,95%CI(-0.33,0.72);WMD=0.24,95%CI(-0.12,0.60);WMD=0.31,95%CI(-0.07,0.69);WMD=0.03,95%CI(-0.29,0.35)]和运动评分[WMD=0.10,95%CI(-0.41,0.62);WMD=0.64,95%CI(0.15,1.12);WMD=0.17,95%CI(-0.37,0.70);WMD=0.03,95%CI(-0.57,0.62)]差异均无统计学意义;ACB组患者的肌力在术后4~8 h、24 h及48 h[WMD=0.45,95%CI(0.25,0.64);WMD=0.38,95%CI(0.14,0.61);WMD=0.41,95%CI(0.18,0.63)]均显著优于FNB组;与FNB组比较,ACB组患者在术后24 h、48 h及72 h的膝关节活动度[WMD=5.01,95%CI(0.78,0.92);WMD=8.74,95%CI(3.54,13.93);WMD=6.65,95%CI(1.97,11.33)]、站立行走试验所需时间[WMD=-55.98,95%CI(-109.60,-2.35)]及术后平均住院时间[WMD=-0.049,95%CI(-0.96,-0.03)]等方面有优势,而在术后补救性阿片类药物用量及术后恶心呕吐发生率等方面差异均无统计学意义。

结论

收肌管阻滞与股神经阻滞在TKA术后镇痛疗效相当,同时收肌管阻滞对股四头肌肌力影响更小,从而有利于患者术后早期活动及功能康复。上述结果尚需更多高质量、大样本及多中心随机对照试验来进一步验证。

Objective

To compare adductor canal block (ACB) with femoral nerve block (FNB) for postoperative analgesic effect and early rehabilitation after total knee arthroplasty (TKA).

Methods

The Cochrane Library, PudMed, EMBASE, CNKI, VIP and Wan Fang were searched to identify randomized controlled trials (RCTs) articles comparing the ACB with the FNB in TKA up to August 2016. Study selection and assessment, data collection and analysis were undertaken by two authors independently. The meta-analysis was performed using Review Manager 5.2.0, and publication bias was evaluated through a funnel plot.

Results

Twelve studies were included, involving nine English studies and three Chinese studies There was a total of 772 cases comparing ACB (n=382) with FNB (n=390). Meta-analysis suggested that the resting VAS scores[WMD=0.20, 95%CI(-0.33, 0.72); WMD=0.24, 95%CI(-0.12, 0.60); WMD=0.31, 95%CI(-0.07, 0.69); WMD=0.03, 95%CI(-0.29, 0.35)] and motion VSA scores[WMD=0.10, 95%CI(-0.41, 0.62); WMD=0.64, 95%CI(0.15, 1.12); WMD=0.17, 95%CI(-0.37, 0.70); WMD=0.03, 95%CI(-0.57, 0.62)]were similar to the ACB group and FNB group at 2-4 h, 6-8 h, 24 h and 48 h. The quadriceps strength in the ACB group was better than that in the FNB group at 4 to 8 h, 24 h and 48 h[WMD=0.45, 95%CI(0.25, 0.64); WMD=0.38, 95%CI(0.14, 0.61); WMD=0.41, 95%CI(0.18, 0.63)]. The range of motion in the ACB group was also better than that in the FNB group at 24 h, 48 h and 72 h[WMD=5.01, 95%CI(0.78, 0.92); WMD=8.74, 95%CI(3.54, 13.93); WMD=6.65, 95%CI(1.97, 11.33)]. Besides, ACB group had advantages in time-up-go test[WMD=-55.98, 95%CI(-109.60, -2.35)] and length of hospital stay[WMD=-0.049, 95%CI(-0.96, -0.03)]. There was no difference in opioid consumption and side effect of nausea and vomiting.

Conclusion

When comparing with FNB, the ACB shows similar postoperative analgesia effects and has advantages in quadriceps strength recovery and promoting early postoperative rehabilitation, but more high-quality RCTs are required for further investigation.

表1 纳入研究的一般资料
表2 纳入研究的质量评价
图1 静息VAS(视觉模拟)评分森林图
图2 运动VAS(视觉模拟)评分森林图
图3 股四头肌肌力森林图
图4 术后ROM(活动范围)森林图
图5 站立行走时间
图6 术后平均住院时间森林图
图7 术后阿片类药物用量森林图
图8 术后恶心呕吐发生率森林图
[1]
Singelyn FJ,Deyaert M,Joris D, et al. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral total knee arthroplasty[J]. Anesth Analg, 1998, 87(1): 88-92.
[2]
Ibrahim MS,Khan MA,Nizam I, et al. Peri-operative interventions producing better functional outcomes and enhanced recovery following total hip and knee arthroplasty: an evidence-based review[J]. BMC Med, 2013, 11: 37-46.
[3]
Webb CA,Mariano ER. Best multimodal analgesic protocol for total knee arthroplasty[J]. Pain Manag, 2015, 5(3): 185-196.
[4]
廖荣宗,冯宗权,周观明, 等. 超声引导下连续股神经阻滞在全膝关节置换术后镇痛及功能锻炼的意义[J/CD]. 中华关节外科杂志(电子版), 2014, 8(6):708-712.
[5]
臧学慧,孙辉,高立华, 等. 股神经阻滞镇痛对全膝关节置换术后早期功能的影响[J/CD]. 中华关节外科杂志(电子版), 2016, 10(2):26-29.
[6]
Widmer BJ,Scholes CJ,Pattullo GG, et al. Is femoral nerve block necessary during total knee arthroplasty? a randomized controlled trial[J]. J Arthroplasty, 2012, 27(10): 1800-1805.
[7]
Paul JE,Arya A,Hurlburt L, et al. Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials[J]. Anesthesiology, 2010, 113(5): 1144-1162.
[8]
Sakai N,Inoue T,Kunugiza Y, et al. Continuous femoral versus epidural block for attainment of 120 degrees knee flexion after total knee arthroplasty: a randomized controlled trial[J]. J Arthroplasty, 2013, 28(5): 807-814
[9]
Albrecht E,Morfey D,Chan V, et al. Single-injection or continuous femoral nerve block for total knee arthroplasty[J]. Clin Orthop Relat Res, 2014, 472(5): 1384-1393.
[10]
Charous MT,Madison SJ,Suresh PJ, et al. Continuous femoral nerve blocks: varying local anesthetic delivery method (bolus versus basal) to minimize quadriceps motor block while maintaining sensory block[J]. Anesthesiology, 2011, 115(4): 774-781.
[11]
Kwofie MK,Shastri UD,Gadsden JC, et al. The effects of ultrasound-guided adductor canal block versus femoral nerve block on quadriceps strength and fall risk: a blinded, randomized trial of volunteers[J]. Reg Anesth Pain Med, 2013, 38(4): 321-325.
[12]
Jaeger P,Nielsen ZJ,Henningsen MH, et al. Adductor canal block versus femoral nerve block and quadriceps strength: a randomized, double-blind, placebo-controlled, crossover study in healthy volunteers[J]. Anesthesiology, 2013, 118(2): 409-415.
[13]
Kim DH,Lin Y,Goytizolo EA, et al. Adductor canal block versus femoral nerve block for total knee arthroplasty: a prospective, randomized, controlled trial[J]. Anesthesiology, 2014, 120(3): 540-550.
[14]
Perlas A,Kirkham KR,Billing R, et al. The impact of analgesic modality on early ambulation following total knee arthroplasty[J]. Reg Anesth Pain Med, 2013, 38(4): 334-339.
[15]
Jenstrup MT,Jaeger P,Lund J, et al. Effects of Adductor-Canal-Blockade on pain and ambulation after total knee arthroplasty: a randomized study[J]. Acta Anaesthesiol Scand, 2012, 56(3): 357-364.
[16]
Shah NA,Jain NP. Is continuous adductor canal block better than continuous femoral nerve block after total knee arthroplasty? Effect on ambulation ability, early functional recovery and pain control: a randomized controlled trial[J]. J Arthroplasty, 2014, 29(11): 2224-2229.
[17]
Grevstad U,Mathiesen O,Valentiner LS, et al. Effect of adductor canal block versus femoral nerve block on quadriceps strength, mobilization, and pain after total knee arthroplasty: a randomized, blinded study[J]. Reg Anesth Pain Med, 2014, 40(1): 3-10.
[18]
Zhang W,Hu Y,Tao Y, et al. Ultrasound-guided continuous adductor canal block for analgesia after total knee replacement[J]. Chin Med J (Engl), 2014, 127(23): 4077-4081.
[19]
Elkassabany NM,Antosh S,Ahmed M, et al. The risk of falls after total knee arthroplasty with the use of a femoral nerve block versus an adductor canal block: a Double-Blinded randomized controlled study[J]. Anesth Analg, 2016, 122(5): 1696-1703.
[20]
Sorensen JK,Jaeger P,Dahl JB, et al. The isolated effect of adductor canal block on quadriceps femoris muscle strength after total knee arthroplasty: a Triple-Blinded, randomized, Placebo-Controlled trial with individual patient analysis[J]. Anesth Analg, 2016, 122(2): 553-558.
[21]
Wiesmann T,Piechowiak K,Duderstadt SA, et al. Continuous adductor canal block versus continuous femoral nerve block after total knee arthroplasty for mobilisation capability and pain treatment: a randomised and blinded clinical trial[J]. Arch Orthop Trauma Surg, 2016, 136(3): 397-406.
[22]
Mudumbai SC,Kim TE,Howard SK, et al. Continuous adductor canal blocks are superior to continuous femoral nerve blocks in promoting early ambulation after TKA[J]. Clin Orthop Relat Res, 2014, 472(5): 1377-1383.
[23]
Sztain JF,Machi AT,Kormylo NJ, et al. Continuous adductor canal versus continuous femoral nerve blocks:relative effects on discharge readiness following unicompartment knee arthroplasty[J]. Reg Anesth Pain Med, 2015, 40(5): 559-567.
[24]
谭振,康鹏德,裴福兴, 等. 多模式镇痛下收肌管与股神经阻滞在全膝关节置换术后初期镇痛及早期康复中的作用[J]. 中华骨科杂志, 2015, 35(9):914-920.
[25]
Jaeger P,Zaric D,Fomsgaard JS, et al. Adductor canal block versus femoral nerve block for analgesia after total knee arthroplasty a randomized, double-blind study[J]. Reg Anesth Pain Med, 2013, 38(6): 526-532.
[26]
Machi AT,Sztain JF,Kormylo NJ, et al. Discharge readiness after tricompartment knee arthroplasty:adductor canal versus femoral continuous nerve blocks-a dual-center, randomized trial[J]. Anesthesiology, 2015, 123(2): 444-456.
[27]
Memtsoudis SG,Yoo D,Stundner O, et al. Subsartorial adductor canal vs femoral nerve block for analgesia after total knee replacement[J]. Int Orthop, 2015, 39(4): 673-680.
[28]
张云慧,岳冬梅,刘清仁, 等. 持续收肌管阻滞对全膝关节置换术后早期活动的影响[J]. 临床麻醉学杂志, 2015, 31(10):966-968.
[29]
刘玥,张燕姿,谭振, 等. 超声引导下收肌管阻滞与股神经阻滞对全膝关节置换术后镇痛的影响[J]. 华西医学, 2014, 29(12):2231-2235.
[30]
Husted H,Jensen CM,Solgaard S, et al. Reduced length of stay following hip and knee arthroplasty in Denmark 2000-2009: from research to implementation[J]. Arch Orthop Trauma Surg, 2012, 132(1): 101-104.
[31]
Valeberg BT,Hovik LH,Gjeilo KH. Relationship between self-reported pain sensitivity and pain after total knee arthroplasty: a prospective study of 71 patients 8 weeks after a standardized fast-track program[J/OL]. J Pain Res, 2016, 9: 625-629.
[32]
Chan EY,Blyth FM,Nairn L, et al. Acute postoperative pain following hospital discharge after total knee arthroplasty[J]. Osteoarthritis Cartilage, 2013, 21(9): 1257-1263.
[33]
肖军,严格,罗裕强, 等. 疼痛对人工膝关节表面置换术后功能康复的影响[J/CD]. 中华关节外科杂志(电子版), 2014, 8(2):160-165.
[34]
Kuang MJ,Xu LY,Ma JX, et al. Adductor canal block versus continuous femoral nerve block in primary total knee arthroplasty: a meta-analysis[J/OL]. Int J Surg, 2016, 31: 17-24.
[35]
Vendittoli PA,Makinen P,Drolet P, et al. A multimodal analgesia protocol for total knee arthroplasty. A randomized, controlled study[J]. J Bone Joint Surg Am, 2006, 88(2): 282-289.
[36]
Lavie LG,Fox MP,Dasa V. Overview of total knee arthroplasty and modern pain control strategies[J]. Curr Pain Headache Rep, 2016, 20(11): 59-64.
[37]
Gao F,Ma J,Sun W, et al. Adductor canal block versus femoral nerve block for analgesia after total knee arthroplasty: a systematic review and meta-analysis[J]. Clin J Pain, 2017, 33(4): 356-368.
[38]
Pelt CE,Anderson AW,Anderson MB, et al. Postoperative falls after total knee arthroplasty in patients with a femoral nerve catheter: can we reduce the incidence?[J]. J Arthroplasty, 2014, 29(6): 1154-1157.
[39]
Burckett-St Laurant D,Peng P,Girón Arango L, et al. The nerves of the adductor canal and the innervation of the knee: an anatomic study[J]. Reg Anesth Pain Med, 2016, 41(3): 321-327.
[40]
Dunaway DJ,Steensen RN,Wiand W, et al. The sartorial branch of the saphenous nerve:its anatomy at the joint line of the knee[J]. Arthroscopy, 2005, 21(5): 547-551.
[41]
Kapoor R,Adhikary SD,Siefring C, et al. The saphenous nerve and its relationship to the nerve to the vastus medialis in and around the adductor canal: an anatomical study[J]. Acta Anaesthesiol Scand, 2012, 56(3): 365-367.
[42]
Hussain N,Ferreri TG,Prusick PJ, et al. Adductor canal block versus femoral canal block for total knee arthroplasty: a Meta-Analysis what does the evidence suggest?[J]. Reg Anesth Pain Med, 2016, 41(3): 314-320.
[43]
Li D,Yang Z,Xie X, et al. Adductor canal block provides better performance after total knee arthroplasty compared with femoral nerve block: a systematic review and meta-analysis[J]. Int Orthop, 2016, 40(5): 925-933.
[44]
Ludwigson JL,Tillmans SD,Galgon RE, et al. A comparison of single shot adductor canal block versus femoral nerve catheter for total knee arthroplasty[J]. J Arthroplasty, 2015, 2015, 30(9 Suppl):68-71.
[45]
Dong CC,Dong SL,He FC. Comparison of adductor canal block and femoral nerve block for postoperative pain in total knee arthroplasty a systematic review and meta-analysis[J/OL]. Medicine (Baltimore), 2016, 95(12): e2983-e2993.
[1] 孙俊锋, 涂家金, 付丹, 蒋满香, 刘金晶, 崔乃硕. 手部烧伤瘢痕挛缩畸形整形术后综合康复联合点阵二氧化碳激光治疗的临床效果[J/OL]. 中华损伤与修复杂志(电子版), 2024, 19(05): 411-415.
[2] 钟锴, 蒋铁民, 张瑞青, 吐尔干艾力·阿吉, 邵英梅, 郭强. 加速康复外科在肝囊型棘球蚴病肝切除术中的应用分析[J/OL]. 中华普通外科学文献(电子版), 2024, 18(06): 425-429.
[3] 代莉, 郭华静, 邓恢伟. 镇痛-伤害性刺激指数指导下无阿片类药物麻醉对腔镜下甲状腺手术患者术后恢复质量的影响[J/OL]. 中华普通外科学文献(电子版), 2024, 18(04): 282-286.
[4] 李月平, 李科, 乔禹铭, 钟美浓. 前列腺热蒸汽消融术医护康一体化快速康复模式初探[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(05): 464-472.
[5] 方辉强, 黄杰, 随冰琰. 腰方肌阻滞与腹横肌平面阻滞对腹股沟疝腹腔镜手术患者术后镇痛效果的影响[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 697-702.
[6] 曹健, 冯高华, 周卫军, 陈诚, 沈王丰, 吴英姿. 补脾益肺膏联合肺康复训练治疗慢性阻塞性肺疾病的临床分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(05): 781-784.
[7] 杨轲, 丁增巴姆, 马静, 李盼盼, 陈婷. 全程无缝隙肺康复训练在单孔胸腔镜肺叶切除术中的临床应用[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(05): 801-804.
[8] 任甜甜, 张玉慧, 祁玲霞, 朱梅冬, 胡佳. 多学科疼痛管理对胸腔镜肺叶切除术后胸痛及应激反应的影响分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(04): 630-633.
[9] 郭少琳, 郭建英, 左秀萍, 高苗. 慢性阻塞性肺疾病康复训练依从性影响因素分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(04): 652-654.
[10] 陈冬冬, 余程冬, 曹晓光. 上肢外骨骼机器人在脑卒中康复中的应用与研究进展[J/OL]. 中华脑科疾病与康复杂志(电子版), 2024, 14(05): 312-317.
[11] 谢浩文, 丁建英, 刘小霞, 冯毅, 姚婧. 椎旁神经阻滞对微创胃切除肥胖患者术中血流、术后应激及康复质量的影响[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 569-573.
[12] 贾玲玲, 滕飞, 常键, 黄福, 刘剑萍. 心肺康复在各种疾病中应用的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 859-862.
[13] 刘芳明, 石秀秀, 唐冲, 张克石, 徐影, 王桂杉, 关振鹏, 李晓. 骨科康复患者对数字疗法应用的知晓度和需求度:一项基于928 份问卷调查结果分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 654-661.
[14] 蔡雨玲, 王刚, 江志伟. 针刺应用于术后肠麻痹的研究进展[J/OL]. 中华针灸电子杂志, 2024, 13(04): 164-168.
[15] 刘晓鹏, 柳聪艳, 杨宁, 蔡琛, 李晓兵, 王红宇, 张思森. 三穴五针联合腹部提压法在机械通气患者肺康复中的疗效[J/OL]. 中华卫生应急电子杂志, 2024, 10(04): 193-198.
阅读次数
全文


摘要