| [1] |
Ethgen O, Bruyère O, Richy F, et al. Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature[J]. J Bone Joint Surg Am, 2004, 86-A(5): 963-974.
|
| [2] |
Kurtz S, Ong K, Lau E, et al. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030[J]. J Bone Joint Surg Am, 2007, 89(4): 780-785.
|
| [3] |
Wong J, Abrishami A, El Beheiry H, et al. Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial[J]. J Bone Joint Surg Am, 2010, 92(15): 2503-2513.
|
| [4] |
Sculco TP, Baldini A, Keating EM. Blood management in total joint arthroplasty[J]. Instr Course Lect, 2005, 54: 51-66.
|
| [5] |
Rasouli MR, Maltenfort MG, Erkocak OF, et al. Blood management after total joint arthroplasty in the United States：19-year trend analysis[J]. Transfusion, 2016, 56(5): 1112-1120.
|
| [6] |
Gomez-Barrena E, Ortega-Andreu M, Padilla-Eguiluz NG, et al. Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial[J]. J Bone Joint Surg Am, 2014, 96(23): 1937-1944.
|
| [7] |
Dunn CJ, Goa KL. Tranexamic acid：a review of its use in surgery and other indications[J]. Drugs, 1999, 57(6): 1005-1032.
|
| [8] |
Samujh C, Falls TD, Wessel R, et al. Decreased blood transfusion following revision total knee arthroplasty using tranexamic acid[J]. J Arthroplasty, 2014, 29(9, S): 182-185.
|
| [9] |
Henry DA, Moxey AJ, Carless PA, et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion[J/OL]. Cochrane Database Syst Rev, 2011 (3): CD001886. doi： 10.1002/14651858.CD001886.pub4. |
| [10] |
Ker K, Prieto-Merino D, Roberts I. Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss[J]. Br J Surg, 2013, 100(10): 1271-1279.
|
| [11] |
CRASH-2 collaborators, Roberts I, Shakur H, et al. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial[J]. Lancet, 2011, 377(9771): 1096-1101, 1101.e1-e2.
|
| [12] |
Simonazzi G, Bisulli M, Saccone G, et al. Tranexamic acid for preventing postpartum blood loss after cesarean delivery: a systematic review and meta-analysis of randomized controlled trials[J]. Acta Obstet Gynecol Scand, 2016, 95(1): 28-37.
|
| [13] |
Adler MS, Brindle W, Burton G, et al. Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: a systematic review and meta-analysis[J]. J Cardiothorac Vasc Anesth, 2011, 25(1): 26-35.
|
| [14] |
Benoni G, Carlsson A, Petersson C, et al. Does tranexamic acid reduce blood loss in knee arthroplasty？[J]. Am J Knee Surg, 1995, 8(3): 88-92.
|
| [15] |
Ishida K, Tsumura N, Kitagawa A, et al. Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty[J]. Int Orthop, 2011, 35(11): 1639-1645.
|
| [16] |
Yue C, Pei F, Yang P, et al. Effect of topical tranexamic acid in reducing bleeding and transfusions in TKA[J]. Orthopedics, 2015, 38(5): 315-324.
|
| [17] |
Gao F, Ma J, Sun W, et al. Topical fibrin sealant versus intravenous tranexamic acid for reducing blood loss following total knee arthroplasty: a systematic review and meta-analysis[J]. Int J Surg, 2016, 32: 31-37.
|
| [18] |
Liu Q, Geng P, Shi L, et al. Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: a systematic review and meta-analysis[J]. Int J Surg, 2018, 54(Pt A): 105-112.
|
| [19] |
Higgins JT. Measuring inconsistency in meta-analyses[J]. BMJ, 2003, 327(7414): 557-560.
|
| [20] |
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias[J]. Biometrics, 1994, 50(4): 1088-1101.
|
| [21] |
Egger M, Davey Smith G, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test[J]. BMJ, 1997, 315(719): 629-634.
|
| [22] |
宝音，王嘎日迪，李晓东．氨甲环酸不同给药途径对膝关节置换失血量的影响[J]．中国矫形外科杂志，2017，25(12)：1096-1101.
|
| [23] |
柴星宇，苏长征，庞涛，等．全膝关节置换后静脉与局部应用氨甲环酸对失血量的影响[J]．中国组织工程研究，2015，19(35)：5604-5609.
|
| [24] |
褚国庆，刘藜箬，闫明童，等．氨甲环酸静脉联合局部用药减少初次单侧膝关节置换出血[J/CD]．中华关节外科杂志(电子版)，2018，12(5)：671-675.
|
| [25] |
段虹昊，马建兵，李辉，等．全膝关节置换术中氨甲环酸不同用法的疗效与安全性研究[J]．实用骨科杂志，2017，23(1)：5-8.
|
| [26] |
高智慧，张帅，郭浩辉，等．关节腔内注射及静脉滴注氨甲环酸对全膝关节置换术后失血的影响[J]．临床骨科杂志，2018，21(1)：59-61.
|
| [27] |
胡文浩．静脉与局部应用氨甲环酸在初次全膝关节置换中的比较[J]．中国组织工程研究，2018，22(3)：356-361.
|
| [28] |
李华贵，常炳营，王伟，等．静脉及关节腔内注射氨甲环酸减少全膝关节置换术后出血的对比研究[J]．中国现代医学杂志，2017，27(22)：117-120.
|
| [29] |
李辉，马建兵，姚舒馨，等．氨甲环酸应用于全膝关节置换术围术期的给药方式比较[J]．中华骨与关节外科杂志，2017，10(1)：37-40.
|
| [30] |
梁洪忠，朱延民．氨甲环酸不同给药方式对全膝关节置换术术后失血量和凝血功能的影响[J]．医学综述，2017，23(2)：414-417.
|
| [31] |
罗太行，古霖，罗世富．联合应用氨甲环酸对TKA术后失血量疗效观察[J]．养生保健指南，2018，16(19)：314-315.
|
| [32] |
潘云春，卢菁，张其亮．静脉及局部应用氨甲环酸对全膝关节置换围术期失血的影响[J]．中国医药导报，2016，13(12)：156-159.
|
| [33] |
孙博，王静悦，李冀．氨甲环酸静脉与局部联合用药对全膝关节置换患者围术期纤溶活性与失血量的影响[J]．河北医学，2019，25(3)：667-671.
|
| [34] |
王庆东，李付彬，徐向峰，等．氨甲环酸术前静脉滴注联合术中关节内注射对全膝关节置换术围手术期失血量的影响[J]．中医正骨，2016，28(1)：24-27.
|
| [35] |
武辉，全健，雷斌．关节腔和静脉联合应用氨甲环酸对人工全膝关节置换术疗效及出血量的影响[J]．安徽医药，2018，22(10)：1983-1986.
|
| [36] |
杨伟臻，张剑锋，胡宝德，等．静脉与关节腔内应用氨甲环酸减少全膝关节置换失血量的疗效对比[J]．中国医学创新，2016，13(27)：1-5.
|
| [37] |
张岩，阚泉，张军伟，等．重度膝骨关节炎患者全膝关节置换术中氨甲环酸静脉注射与关节腔内注射的止血效果对比观察[J]．山东医药，2019，59(21)：58-60.
|
| [38] |
Abdel MP, Chalmerset BP, Tauntonal MJ, et al. Intravenous versus topical tranexamic acid in total knee arthroplasty：both effective in a randomized clinical trial of 640 patients[J]. J Bone Joint Surg Am, 2018, 100(12): 1023-1029.
|
| [39] |
Jy C, Chin PL, Moo IH, et al. Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: a double-blinded randomised controlled noninferiority trial[J]. Knee, 2016, 23(1): 152-156.
|
| [40] |
Digas G, Koutsogiannis I, Meletiadis G, et al. Intra-articular injection of tranexamic acid reduce blood loss in cemented total knee arthroplasty[J]. Eur J Orthop Surg Traumatol, 2015, 25(7): 1181-1188.
|
| [41] |
Drosos GI, Ververidis A, Valkanis C, et al. A randomized comparative study of topical versus intravenous tranexamic acid administration in enhanced recovery after surgery (ERAS) total knee replacement[J]. J Orthop, 2016, 13(3): 127-131.
|
| [42] |
George J, Eachempati KK, Subramanyam KN, et al. The comparative efficacy and safety of topical and intravenous tranexamic acid for reducing perioperative blood loss in total knee arthroplasty- a randomized controlled non-inferiority trial[J]. Knee, 2018, 25(1): 185-191.
|
| [43] |
Gomez-Barrenae G, Ortega-Andreu M, Padilla-Eguiluz NG, et al. Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement：a double-blind, randomized, controlled, noninferiority clinical trial[J]. J Bone Joint Surg Am, 2014, 96(23): 1937-1944.
|
| [44] |
Huang Z, Ma J, Shen B, et al. Combination of intravenous and topical application of tranexamic acid in primary total knee arthroplasty: a prospective randomized controlled trial[J]. J Arthroplasty, 2014, 29(12): 2342-2346.
|
| [45] |
Jain NP, Nisthane PP, Shah NA. Combined administration of systemic and topical tranexamic acid for total knee arthroplasty: can it be a better regimen and yet safe? A randomized controlled trial[J]. J Arthroplasty, 2016, 31(2): 542-547.
|
| [46] |
Jules-Elyseekm J, Tseng A, Sculco TP, et al. Comparison of topical and intravenous tranexamic acid for total knee replacement：a randomized double-blinded controlled study of effects on tranexamic acid levels and thrombogenic and inflammatory marker levels[J]. J Bone Joint Surg Am, 2019, 101(23): 2120-2128.
|
| [47] |
Lee SY, Chong S, Balasubramanian D, et al. What is the ideal route of administration of tranexamic acid in TKA? A randomized controlled trial[J]. Clin Orthop Relat Res, 2017, 475(8): 1987-1996.
|
| [48] |
Lin SY, Chen CH, Fu YC, et al. The efficacy of combined use of intraarticular and intravenous tranexamic acid on reducing blood loss and transfusion rate in total knee arthroplasty[J]. J Arthroplasty, 2015, 30(5): 776-780.
|
| [49] |
Maniar RN, Kumar G, Singhi T, et al. Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients[J]. Clin Orthop Relat Res, 2012, 470(9): 2605-2612.
|
| [50] |
May JH, Rieser GR, Williams CG, et al. The assessment of blood loss during total knee arthroplasty when comparing intravenous vs intracapsular administration of tranexamic acid[J]. J Arthroplasty, 2016, 31(11): 2452-2457.
|
| [51] |
Nielsen CS, Jans Ø, Ørsnes T, et al. Combined intra-articular and intravenous tranexamic acid reduces blood loss in total knee arthroplasty: a randomized, double-blind, placebo-controlled trial[J]. J Bone Joint Surg Am, 2016, 98(10): 835-841.
|
| [52] |
Özta S, Öztürk A, Akalin Y, et al. The effect of local and systemic application of tranexamic acid on the amount of blood loss and allogeneic blood transfusion after total knee replacement[J]. Acta Orthop Belg, 2015, 81(4): 698-707.
|
| [53] |
Patel JN, Spanyer JM, Smith LS, et al. Comparison of intravenous versus topical tranexamic acid in total knee arthroplasty: a prospective randomized study[J]. J Arthroplasty, 2014, 29(8): 1528-1531.
|
| [54] |
Sarzaeem MM, Razi M, Kazemian G, et al. Comparing efficacy of three methods of tranexamic acid administration in reducing hemoglobin drop following total knee arthroplasty[J]. J Arthroplasty, 2014, 29(8): 1521-1524.
|
| [55] |
Seo JG, Moon YW, Park SH, et al. The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty[J]. Knee Surg Sports Traumatol Arthrosc, 2013, 21(8): 1869-1874.
|
| [56] |
Song EK, Seon JK, Prakash J, et al. Combined administration of IV and topical tranexamic acid is not superior to either individually in primary navigated TKA[J]. J Arthroplasty, 2017, 32(1): 37-42.
|
| [57] |
Subramanyam KN, Khanchandani P, Tulajaprasad PV, et al. Efficacy and safety of intra-articular versus intravenous tranexamic acid in reducing perioperative blood loss in total knee arthroplasty: a prospective randomized double-blind equivalence trial[J]. Bone Joint J, 2018, 100-B(2): 152-160.
|
| [58] |
Tzatzairis TK, Drosos GI, Kotsios SE, et al. Intravenous vs topical tranexamic acid in total knee arthroplasty without tourniquet application: a randomized controlled study[J]. J Arthroplasty, 2016, 31(11): 2465-2470.
|
| [59] |
Uğurlu M, Aksekili MA, Çăglar C, et al. Effect of topical and intravenously applied tranexamic acid compared to control group on bleeding in primary unilateral total knee arthroplasty[J]. J Knee Surg, 2017, 30(2): 152-157.
|
| [60] |
Wang J, Wang Q, Zhang X, et al. Intra-articular application is more effective than intravenous application of tranexamic acid in total knee arthroplasty: a prospective randomized controlled trial[J]. J Arthroplasty, 2017, 32(11): 3385-3389
|
| [61] |
Wei W, Dang S, Duan D, et al. Comparison of intravenous and topical tranexamic acid in total knee arthroplasty[J/OL]. BMC Musculoskelet Disord, 2018, 19(1): 191. doi： 10.1186/s12891-018-2122-7. |
| [62] |
Hiippala ST, Strid LJ, Wennerstrand MI, et al. Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty[J]. Anesth Analg, 1997, 84(4): 839-844.
|
| [63] |
Xie J, Hu Q, Huang Q, et al. Comparison of intravenous versus topical tranexamic acid in primary total hip and knee arthroplasty: an updated meta-analysis[J]. Thromb Res, 2017, 153: 28-36.
|
| [64] |
Panteli M, Papakostidis C, Dahabreh Z, et al. Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis[J]. Knee, 2013, 20(5): 300-309.
|
| [65] |
Andersson L, Nilsson IM, Niléhn JE, et al. Experimental and clinical studies on AMCA, the antifibrinolytically active isomer of p-aminomethyl cyclohexane carboxylic acid[J]. Scand J Haematol, 1965, 2(3): 230-247.
|
| [66] |
Sukeik M, Alshryda S, Haddad FS, et al. Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement[J]. J Bone Joint Surg Br, 2011, 93B(1): 39-46.
|
| [67] |
Aglietti P, Baldini A, Vena LM, et al. Effect of tourniquet use on activation of coagulation in total knee replacement[J]. Clin Orthop Relat Res, 2000, (371): 169-177.
|
| [68] |
Sun X, Dong Q, Zhang YG. Intravenous versus topical tranexamic acid in primary total hip replacement: a systemic review and meta-analysis[J]. Int J Surg, 2016, 32: 10-18.
|
| [69] |
Benoni G, Fredin H, Knebel R, et al. Blood conservation with tranexamic acid in total hip arthroplasty - a randomized, double-blind study in 40 primary operations[J]. Acta Orthop Scand, 2001, 72(5): 442-448.
|