切换至 "中华医学电子期刊资源库"

中华关节外科杂志(电子版) ›› 2025, Vol. 19 ›› Issue (05) : 609 -614. doi: 10.3877/cma.j.issn.1674-134X.2025.05.011

综述

髋关节局部解剖形态与髋关节骨关节炎的关系研究进展
王帆1,2, 袁鹏1,2, 弓一心1,2, 张世杰1,2, 张国豪1,2, 焦强1,2,()   
  1. 1030001 太原,山西医科大学第二医院骨科
    2030001 太原,骨与软组织损伤修复山西省重点实验室
  • 收稿日期:2025-03-18 出版日期:2025-10-01
  • 通信作者: 焦强
  • 基金资助:
    山西省留学人员科技活动择优资助项目(重点)(20210006)

Research progress on relationship between local hip anatomy and hip osteoarthritis

Fan Wang1,2, Peng Yuan1,2, Yixin Gong1,2, Shijie Zhang1,2, Guohao Zhang1,2, Qiang Jiao1,2,()   

  1. 1Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan 030001, China
    2Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Taiyuan 030001, China
  • Received:2025-03-18 Published:2025-10-01
  • Corresponding author: Qiang Jiao
引用本文:

王帆, 袁鹏, 弓一心, 张世杰, 张国豪, 焦强. 髋关节局部解剖形态与髋关节骨关节炎的关系研究进展[J/OL]. 中华关节外科杂志(电子版), 2025, 19(05): 609-614.

Fan Wang, Peng Yuan, Yixin Gong, Shijie Zhang, Guohao Zhang, Qiang Jiao. Research progress on relationship between local hip anatomy and hip osteoarthritis[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2025, 19(05): 609-614.

髋关节骨关节炎是一种常见的退行性疾病,其具体发病机制仍不明确,但目前有大量研究表明髋关节局部解剖异常是髋骨关节炎发生的危险因素。髋臼发育不良、髋关节撞击综合征等畸形状态可能与髋骨关节的发生及进展有重要关联。本综述从影像学的角度总结了与髋骨关节炎相关的髋臼发育不良、髋关节撞击综合征、髋内外翻等畸形的影像学评估方法、意义及研究进展,以期使读者加深对髋骨关节炎的认识,为临床诊断和治疗提供指导。

Hip osteoarthritis is a common degenerative joint disease, and the exact pathogenesis remains incompletely understood. However, substantial evidence suggests that local anatomical abnormalities of the hip joint are risk factors for the development of hip osteoarthritis. Morphological abnormalities such as acetabular dysplasia and femoroacetabular impingement syndrome may play important roles in the onset and progression of hip osteoarthritis. From an imaging perspective, this review summarized the radiographic assessment methods, clinical significance, and recent research advances related to hip morphological abnormalities—including acetabular dysplasia, femoroacetabular impingement, and coxa vara/valga—associated with hip osteoarthritis. The aim is to enhance the understanding of hip osteoarthritis and provide guidance for clinical diagnosis and treatment.

图1 骨盆正位片上髋关节周围重要影像学参数测量方法
Figure 1 Pivotal radiographic parameters measurements around the hip joint on anteroposterior view of pelvis
表1 骨盆正位片上髋关节周围影像学参数测量方法
Table 1 Measurements for radiographic parameters around the hip joint on anteroposterior pelvic radiograph
[1]
吴惠一, 袁琴, 张洋, 等. 1990―2019年我国肌肉骨骼疾病负担分析[J]. 中华疾病控制杂志, 2023, 27(6): 655-661.
[2]
Hall M, van der Esch M, Hinman RS, et al. How does hip osteoarthritis differ from knee osteoarthritis? [J]. Osteoarthritis Cartilage, 2022, 30(1): 32-41.
[3]
Abdulrahim H, Jiao Q, Swain S, et al. Constitutional morphological features and risk of hip osteoarthritis: a case-control study using standard radiographs[J]. Ann Rheum Dis, 2021, 80(4): 494-501.
[4]
Čengić T, Trkulja V, Pavelić SK, et al. Association of TGFB1 29C/T and IL6-572G/C polymorphisms with developmental hip dysplasia: a case-control study in adults with severe osteoarthritis[J]. Int Orthop, 2015, 39(4): 793-798.
[5]
Jacobsen S, Sonne-Holm S. Hip dysplasia: a significant risk factor for the development of hip osteoarthritis. A cross-sectional survey [J]. Rheumatology, 2005, 44(2): 211-218.
[6]
Reijman M, Hazes JW, Pols HP, et al. Acetabular dysplasia predicts incident osteoarthritis of the hip: the Rotterdam study[J]. Arthritis Rheum, 2005, 52(3): 787-793.
[7]
Jacobsen S, Sonne-Holm S, Søballe K, et al. Hip dysplasia and osteoarthrosis: a survey of 4151 subjects from the Osteoarthrosis Substudy of the Copenhagen City Heart Study [J]. Acta Orthop, 2005, 76(2): 149-158.
[8]
Daysal GA, Goker B, Gonen E, et al. The relationship between hip joint space width, center edge angle and acetabular depth [J]. Osteoarthritis Cartilage, 2007, 15(12): 1446-1451.
[9]
McWilliams DF, Doherty SA, Jenkins WD, et al. Mild acetabular dysplasia and risk of osteoarthritis of the hip: a case-control study [J]. Ann Rheum Dis, 2010, 69(10): 1774-1778.
[10]
Lee YK, Chung CY, Koo KH, et al. Measuring acetabular dysplasia in plain radiographs [J]. Arch Orthop Trauma Surg, 2011, 131(9): 1219-1226.
[11]
Herfkens J, van Buuren MMA, Riedstra NS, et al. Adding false-profile radiographs improves detection of developmental dysplasia of the hip, data from the CHECK cohort [J]. J Hip Preserv Surg, 2022, 9(1): 3-9.
[12]
Ganz R, Parvizi J, Beck M, et al. Femoroacetabular impingement: a cause for osteoarthritis of the hip[J]. Clin Orthop Relat Res, 2003(417): 112-120.
[13]
Beck M, Kalhor M, Leunig M, et al. Hip morphology influences the pattern of damage to the acetabular cartilage: femoroacetabular impingement as a cause of early osteoarthritis of the hip[J]. J Bone Joint Surg Br, 2005, 87(7): 1012-1018.
[14]
Bittersohl B, Steppacher S, Haamberg T, et al. Cartilage damage in femoroacetabular impingement (FAI): preliminary results on comparison of standard diagnostic vs delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC)[J]. Osteoarthritis Cartilage, 2009, 17(10): 1297-1306.
[15]
Nötzli HP, Wyss TF, Stoecklin CH, et al. The contour of the femoral head-neck junction as a predictor for the risk of anterior impingement [J]. J Bone Joint Surg Br, 2002, 84(4): 556-560.
[16]
Gosvig KK, Jacobsen S, Palm H, et al. A new radiological index for assessing asphericity of the femoral head in cam impingement [J]. J Bone Joint Surg Br, 2007, 89(10): 1309-1316.
[17]
Mascarenhas VV, Castro MO, Diana Afonso P, et al. The Lisbon Agreement on femoroacetabular impingement imaging-part 2: general issues, parameters, and reporting [J]. Eur Radiol, 2021, 31(7): 4634-4651.
[18]
Mascarenhas VV, Caetano A, Dantas P, et al. Advances in FAI imaging: a focused review [J]. Curr Rev Musculoskelet Med, 2020, 13(5): 622-640.
[19]
Reichenbach S, Leunig M, Werlen S, et al. Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage: a cross-sectional study in young men[J]. Arthritis Rheum, 2011, 63(12): 4023-4030.
[20]
Faber BG, Ebsim R, Saunders FR, et al. Cam morphology but neither acetabular dysplasia nor pincer morphology is associated with osteophytosis throughout the hip: findings from a cross-sectional study in UK Biobank[J]. Osteoarthritis Cartilage, 2021, 29(11): 1521-1529.
[21]
Faber BG, Bredbenner TL, Baird D, et al. Subregional statistical shape modelling identifies lesser trochanter size as a possible risk factor for radiographic hip osteoarthritis, a cross-sectional analysis from the Osteoporotic Fractures in Men Study[J]. Osteoarthritis Cartilage, 2020, 28(8): 1071-1078.
[22]
Gielis WP, Weinans H, Welsing PJ, et al. An automated workflow based on hip shape improves personalized risk prediction for hip osteoarthritis in the CHECK study[J]. Osteoarthritis Cartilage, 2020, 28(1): 62-70.
[23]
Tang J, van Buuren MMA, Riedstra NS, et al. Cam morphology is strongly and consistently associated with development of radiographic hip osteoarthritis throughout 4 follow-up visits within 10 years[J]. Osteoarthritis Cartilage, 2023, 31(12): 1650-1656.
[24]
Agricola R, Heijboer MP, Roze RH, et al. Pincer deformity does not lead to osteoarthritis of the hip whereas acetabular dysplasia does: acetabular coverage and development of osteoarthritis in a nationwide prospective cohort study (CHECK)[J]. Osteoarthritis Cartilage, 2013, 21(10): 1514-1521.
[25]
Lee JS, Gillinov SM, Siddiq BS, et al. Association between global overcoverage and long-term survivorship, chondrolabral junction breakdown, and reduced joint space width: minimum 8-year follow-up [J]. Am J Sports Med, 2025, 53(4): 900-910.
[26]
Casartelli NC, Maffiuletti NA, Valenzuela PL, et al. Is hip morphology a risk factor for developing hip osteoarthritis? A systematic review with meta-analysis[J]. Osteoarthritis Cartilage, 2021, 29(9): 1252-1264.
[27]
Wright D, Whyne C, Hardisty M, et al. Functional and anatomic orientation of the femoral head [J]. Clin Orthop Relat Res, 2011, 469(9): 2583-2589.
[28]
Doherty M, Courtney P, Doherty S, et al. Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case-control study[J]. Arthritis Rheum, 2008, 58(10): 3172-3182.
[29]
Moore RJ, Fazzalari NL, Manthey BA, et al. The relationship between head-neck-shaft angle, calcar width, articular cartilage thickness and bone volume in arthrosis of the hip[J]. Br J Rheumatol, 1994, 33(5): 432-436.
[30]
Wiberg, G. Studies on Dysplastic Acetabula and Congenital Subluxation of the Hip Joint with Special Reference to the Complication of Osteo-Arthritis [M]. Acta Chirurgica Scandinavica, 1939, 83: 5–131.
[31]
Davila-Parrilla AD, Wylie J, O’Donnell C, et al. Reliability of and correlation between measurements of acetabular morphology[J/OL]. Orthopedics, 2018, 41(5): e629-e635. DOI:10.3928/01477447-20180711-01.
[32]
Mittal A, Bomar JD, Jeffords ME, et al. Defining the lateral edge of the femoroacetabular articulation: correlation analysis between radiographs and computed tomography[J]. J Child Orthop, 2016, 10(5): 365-370.
[33]
Ogata S, Moriya H, Tsuchiya K, et al. Acetabular cover in congenital dislocation of the hip[J]. J Bone Joint Surg Br, 1990, 72(2): 190-196.
[34]
Shin CH, Yang E, Lim C, et al. Which acetabular landmarks are the most useful for measuring the acetabular index and center-edge angle in developmental dysplasia of the hip? A comparison of two methods [J]. Clin Orthop Relat Res, 2020, 478(9): 2120-2131.
[35]
Murphy MM, Atkins PR, Kobayashi EF, et al. Assessment of acetabular morphology using the acetabular anterior center-edge angle on modified false-profile radiographs [J]. Arthroscopy, 2019, 35(11): 3060-3066.
[36]
Meyer DC, Beck M, Ellis T, et al. Comparison of six radiographic projections to assess femoral head/neck asphericity[J]. Clin Orthop Relat Res, 2006, 445: 181-185.
[37]
Hellman MD, Mascarenhas R, Gupta A, et al. The false-profile view may be used to identify cam morphology[J]. Arthroscopy, 2015, 31(9): 1728-1732.
[38]
Paul Dijkstra H, Auliffe SM, Ardern CL, et al. Oxford consensus on primary cam morphology and femoroacetabular impingement syndrome: part 1-definitions, terminology, taxonomy and imaging outcomes[J]. Br J Sports Med, 2022, 57(6): 325-341.
[39]
Gregory JS, Testi D, Stewart A, et al. A method for assessment of the shape of the proximal femur and its relationship to osteoporotic hip fracture[J]. Osteoporos Int, 2004, 15(1): 5-11.
[40]
Gregory JS, Waarsing JH, Day J, et al. Early identification of radiographic osteoarthritis of the hip using an active shape model to quantify changes in bone morphometric features: can hip shape tell us anything about the progression of osteoarthritis?[J]. Arthritis Rheum, 2007, 56(11): 3634-3643.
[41]
Barr RJ, Gregory JS, Yoshida K, et al. Significant morphological change in osteoarthritic hips identified over 6-12 months using statistical shape modelling [J]. Osteoarthritis Cartilage, 2018, 26(6): 783-789.
[42]
Agricola R, Leyland KM, Bierma-Zeinstra SMA, et al. Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford)[J]. Rheumatology, 2015, 54(11): 2033-2041.
[43]
Nelson AE, Liu F, Lynch JA, et al. Association of incident symptomatic hip osteoarthritis with differences in hip shape by active shape modeling: the Johnston County Osteoarthritis Project[J]. Arthritis Care Res, 2014, 66(1): 74-81.
[44]
An H, Marron JS, Schwartz TA, et al. Novel statistical methodology reveals that hip shape is associated with incident radiographic hip osteoarthritis among African American women[J]. Osteoarthritis Cartilage, 2016, 24(4): 640-646.
[45]
van Buuren MA, Arden NK, Bierma-Zeinstra SA, et al. Statistical shape modeling of the hip and the association with hip osteoarthritis: a systematic review[J]. Osteoarthritis Cartilage, 2021, 29(5): 607-618.
[46]
Ida T, Nakamura Y, Hagio T, et al. Prevalence and characteristics of cam-type femoroacetabular deformity in 100 hips with symptomatic acetabular dysplasia: a case control study[J/OL]. J Orthop Surg Res, 2014, 9: 93. DOI:10.1186/s13018-014-0093-4.
[47]
Heppenstall SV, Ebsim R, Saunders FR, et al. Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: Findings from a cross-sectional study in UK Biobank[J]. Osteoarthr Cartil, 2023, 31(12): 1627-1635.
[48]
Riedstra NS, Vinge R, Herfkens J, et al. Acetabular dysplasia and the risk of developing hip osteoarthritis at 2, 5, 8, and 10 years follow-up in a prospective nationwide cohort study (CHECK)[J/OL]. Semin Arthritis Rheum, 2023, 60: 152194. DOI:10.1016/j.semarthrit.2023.152194.
[1] 何雪威, 廉华, 王宁, 方晓红. 实时动态三维无痛输卵管超声造影在临床中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2025, 22(01): 39-45.
[2] 郑永乐, 庞祖才, 陈家敏, 孙丙银. 骨碎补总黄酮抑制牵张成骨模型骨质疏松的作用研究[J/OL]. 中华关节外科杂志(电子版), 2024, 18(05): 604-608.
[3] 张永威, 刘玉华. 利用列线图区分0~12岁社区获得性肺炎患儿肺炎支原体和病毒感染的探索性研究[J/OL]. 中华妇幼临床医学杂志(电子版), 2025, 21(02): 180-188.
[4] 高思勇, 郭彦君, 陈晖璐, 邓飞龙, 宫苹, 王天璐. 骨结合过程中种植体周血管时空分布的观测研究[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(01): 22-29.
[5] 陈思敏, 毛杰, 杜潇利, 张树泽. CT 与生物电阻抗法测定胃癌患者骨骼肌质量的比较研究[J/OL]. 中华普通外科学文献(电子版), 2025, 19(01): 28-33.
[6] 谢汶歆, 马乐, 刘晔, 曹晓明, 张万春. 前列腺特异性膜抗原PET/CT在肾癌诊疗中的应用价值[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(05): 514-519.
[7] 郑小龙, 李挺, 隋永健, 徐辉. 疝囊进入阴囊的腹股沟直疝CT表现[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(05): 559-562.
[8] 王芳, 刘达, 左智炜, 盛金平, 陈庭进, 蒋锐. 定量CT与双能X线骨密度仪对骨质疏松诊断效能比较的Meta分析[J/OL]. 中华老年骨科与康复电子杂志, 2024, 10(06): 363-371.
[9] 高广涵, 张耀南, 石磊, 王林, 王飞, 郑子天, 王鸿禹, 郭民政, 薛庆云. 膝骨关节炎患者前交叉韧带功能影像学影响因素分析[J/OL]. 中华老年骨科与康复电子杂志, 2024, 10(05): 301-307.
[10] 陈倩倩, 袁晨, 刘基, 尹婷婷. 多层螺旋CT 参数、癌胚抗原、错配修复基因及病理指标对结直肠癌预后的影响[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 507-511.
[11] 张立俊, 孙存杰, 胡春峰, 孟冲, 张辉. MSCT、DCE-MRI 评估术前胃癌TNM 分期的准确性研究[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 519-523.
[12] 袁梦晨, 刘译阳, 赵帅, 陈林, 高宇, 肖晓燕, 尤亚茹, 梁何俊, 高剑波. 增强CT的列线图在鉴别EB病毒相关的胃淋巴上皮瘤样癌与胃腺癌中的应用[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(02): 107-113.
[13] 孙兆男, 何江凯, 黄文鹏, 胡晓煜, 黄勇, 王霄英. 伪膜性结肠炎的CT表现及鉴别诊断[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(02): 172-176.
[14] 尤亚茹, 刘译阳, 李莉明, 赵帅, 袁梦晨, 黄清博, 高剑波. 多层螺旋CT增强扫描对伴有肝转移的胃肝样腺癌的诊断价值[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(01): 21-27.
[15] 赵莉, 张敏伟, 于海侠, 张宇萌, 丰金岭, 李德春. 组织标记夹置入在评估乳腺癌术前新辅助化疗疗效中的应用价值[J/OL]. 中华介入放射学电子杂志, 2024, 12(02): 166-170.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?