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中华关节外科杂志(电子版) ›› 2023, Vol. 17 ›› Issue (06) : 827 -833. doi: 10.3877/cma.j.issn.1674-134X.2023.06.010

综述

细菌培养阴性的假体周围感染诊治的最新进展
李培杰, 乔永杰, 张浩强, 曾健康, 谭飞, 李嘉欢, 王静, 周胜虎()   
  1. 730030 兰州,甘肃中医药大学;730050 兰州,解放军联勤保障部队第九四〇医院关节外科
    730050 兰州,解放军联勤保障部队第九四〇医院关节外科
    730030 兰州,甘肃中医药大学
  • 收稿日期:2022-12-22 出版日期:2023-12-01
  • 通信作者: 周胜虎
  • 基金资助:
    甘肃省重点研发计划(21YF5FA154); 甘肃省青年科技基金(20JR5RA588); 甘肃省青年科技基金(21JR7RA014); 部队专项培育项目(2021YXKY014)

Progress in diagnosis and treatment of periprosthetic infection with negative bacterial culture

Peijie Li, Yongjie Qiao, Haoqiang Zhang, Jiankang Zeng, Fei Tan, Jiahuan Li, Jing Wang, Shenghu Zhou()   

  1. Gansu University of Traditional Chinese Medicine, Lanzhou 730030, China; No. 940 Hospital of the Joint Logistics Support Force of the Chinese people's Liberation Army, Lanzhou 730050, China
    No. 940 Hospital of the Joint Logistics Support Force of the Chinese people's Liberation Army, Lanzhou 730050, China
    Gansu University of Traditional Chinese Medicine, Lanzhou 730030, China
  • Received:2022-12-22 Published:2023-12-01
  • Corresponding author: Shenghu Zhou
引用本文:

李培杰, 乔永杰, 张浩强, 曾健康, 谭飞, 李嘉欢, 王静, 周胜虎. 细菌培养阴性的假体周围感染诊治的最新进展[J]. 中华关节外科杂志(电子版), 2023, 17(06): 827-833.

Peijie Li, Yongjie Qiao, Haoqiang Zhang, Jiankang Zeng, Fei Tan, Jiahuan Li, Jing Wang, Shenghu Zhou. Progress in diagnosis and treatment of periprosthetic infection with negative bacterial culture[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(06): 827-833.

假体周围感染(PJI)是人工关节置换术后最严重的并发症之一。尽管医学领域已经做出了广泛的努力来提高细菌的阳性培养率,但假阴性率的培养结果仍然较高。在缺乏特定微生物的情况下,PJI的正确诊断、手术方式的选择以及抗生素的使用都将面临重大的挑战。因此,提高PJI的阳性培养率显得尤其重要。在这篇综述中,就近年来关于PJI诊治的文章进行简要分析,以期提高临床上培养阴性的PJI的诊治率。

Periprosthetic joint infection (PJI) is one of the most serious complications after artificial joint replacement. Although extensive efforts have been made in the medical field to increase positive culture rates of bacteria, culture results for false negative rates are still high. In the absence of specific microorganisms, the correct diagnosis of PJI, the choice of surgical modality, and the use of antibiotics will present significant challenges. Therefore, it is particularly important to increase the positive culture rate of PJI. In this review, a brief analysis of recent articles on the diagnosis and treatment of PJI was carried out in order to improve the diagnosis and treatment rate of clinically negative PJI.

表1 分子方法特点比较
Table 1 Comparison of molecular methods
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