切换至 "中华医学电子期刊资源库"

中华关节外科杂志(电子版) ›› 2018, Vol. 12 ›› Issue (03) : 429 -432. doi: 10.3877/cma.j.issn.1674-134X.2018.03.024

所属专题: 经典病例 文献

个案报道

髌骨软骨母细胞瘤病例报告1例
赵立明1, 狄正林1,(), 章军辉1, 陶崑1, 曾智敏1, 凌晶1   
  1. 1. 315040 宁波市第六医院关节外科
  • 收稿日期:2017-08-22 出版日期:2018-06-01
  • 通信作者: 狄正林

Case report of chondroblastoma in patella

Liming Zhao1, Zhenglin Di1(), Junhui Zhang1   

  • Received:2017-08-22 Published:2018-06-01
  • Corresponding author: Zhenglin Di
引用本文:

赵立明, 狄正林, 章军辉, 陶崑, 曾智敏, 凌晶. 髌骨软骨母细胞瘤病例报告1例[J]. 中华关节外科杂志(电子版), 2018, 12(03): 429-432.

Liming Zhao, Zhenglin Di, Junhui Zhang. Case report of chondroblastoma in patella[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2018, 12(03): 429-432.

图1 男,19岁,左髌骨软骨母细胞瘤影像学检查图像。图A、B 术前轴、侧位X线片,示左髌骨上部不规则溶骨性破坏,有骨性分隔和点状钙化,髌股关节间隙正常;图C 术前横断位CT扫描,示左髌骨中央部低密度溶骨灶,伴点状钙化,骨皮质变薄,局部连续性中断;图D,E 术前矢状面MRI,T1WI示混杂的低信号,横断面T2WI中等到高信号,周围边界较清晰,关节腔未受侵袭;图F 术后1个月复查X线侧位相示左髌骨病灶植骨充分,并有部分新骨形成;图G 术后24个月复查X线片示左髌骨植骨区生成新骨,未见异体骨吸收
图2 术中切除肿瘤组织的HE染色。图A  示大量的肿瘤细胞散在分布于骨小梁周围(×40);图B 示大量软骨母细胞和破骨样多核巨细胞,其间可见淡红染的软骨样基质。软骨母细胞境界清除,胞质透明,呈圆形、卵圆形或肾形,染色质稀疏分布,核仁不明显,部分可见核纵向沟(×100)
[1]
Xu H, Nugent D, Monforte HL, et al. Chondroblastoma of bone in the extremities: a multicenter retrospective study[J]. J Bone Joint Surg Am, 2015, 97(11):925-931.
[2]
程强,黄伟.髌骨软骨母细胞瘤诊断及治疗进展[J].中国骨伤,2013,26(12):1059-1062.
[3]
张景峰,王跃.WHO骨肿瘤分类第四版:解读与比较[J]. 中华骨科杂志,2015, 35(9):975-979.
[4]
Xie C, Jeys L, James SL. Radiofrequency ablation of chondroblastoma: long-term clinical and imaging outcomes[J]. Eur Radiol, 2015, 25(4):1127-1134.
[5]
Yang J, Tian W, Zhu X, et al.Chondroblastoma in the long bone diaphysis: a report of two cases with literature review[J]. Chin J Cancer, 2012,31(5):257-264.
[6]
Mashhour MA, Abdel Rahman M. Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery[J]. Int Orthop, 2014, 38(5):1019-1024.
[7]
赵资坚,邹育才,刘梦璋,等.瘤腔内钢板支撑联合骨水泥填充重建膝关节周围骨巨细胞瘤扩大刮除后骨缺损[J/CD].中华关节外科杂志(电子版),2013,7(06):801-805.
[8]
Fadel RJ. A rare case of chondroblastoma patella in a jumping athlete[J]. J Ky Med Assoc, 1985, 83(3):133-135.
[9]
Suneja R, Grimer RJ, Belthur M, et al. Chondroblastoma of bone: long-term results and functional outcome after intralesional curettage[J]. J Bone Joint Surg Br, 2005, 87(7):974-978.
[10]
Lehner B, Witte D, Weiss S. Clinical and radiological long-term results after operative treatment of chondroblastoma[J]. Arch Orthop Trauma Surg, 2011, 131(1):45-52.
[11]
Remagen W, Schäfer R, Roggatz J. Chondroblastoma of the patella[J]. Skeletal Radiol, 1980, 96(2):157-158.
[12]
Tomoyuki K, Susa M, Nakayama R, et al. Secondary aneurysmal bone cyst following chondroblastoma of the patella[J]. Rare Tumors, 2013, 5(3):146-148.
[13]
赵立明,苗军,胡永成.骨巨细胞瘤多学科联合的诊治进展[J]. 天津医科大学学报,2016(1):90-92.
[14]
赵立明,徐明,胡永成,等.376例膝关节周围骨巨细胞瘤的临床特征分析[J].中华骨科杂志,2015,35(2):97-104.
[15]
刘志.髌骨软骨母细胞瘤1例[J].中国医学影像技术,2001,17(5):453-453.
[16]
Dhanda S, Menon S, Gulia A. A typical giant chondroblastoma mimicking a chondrosarcoma[J]. J Cancer Res Ther, 2015, 11(3):660-660.
[17]
Cleven AH, Höcker S, Briaire-De Bruijn I, et al. Mutation analysis of H3F3A and H3F3B as a diagnostic tool for giant cell tumor of bone and chondroblastoma[J]. Am J Surg Pathol, 2015, 39(11):1576-1583.
[18]
Aycan OE, Vanel D, Righi A, et al. Chondroblastoma-like osteosarcoma: a case report and review[J]. Skeletal Radiol, 2015, 44(6):869-873.
[19]
王雪梅,王丽萍,牛春波,等.髌骨软骨母细胞瘤的临床病理及文献复习[J].中国实验诊断学,2012,16(05):907-909.
[20]
王武炼,陈嵘,肖莉莉,等.髌骨软骨母细胞瘤合并骨囊肿一例[J].中国骨与关节杂志,2012,01(04):440-442.
[21]
杨艳丽,刘斌,邢传平,等.髌骨软骨母细胞瘤临床病理观察[J].诊断病理学杂志,2009,16(5):361-364.
[22]
王进,吴晔,杨国华,等.原位微波灭活瘤段+重建治疗骨巨细胞瘤的临床观察[J/CD].中华关节外科杂志(电子版),2012,6(1):71-74.
[23]
Rybak LD, Rosenthal DI, Wittig JC. Chondroblastoma: radiofrequency ablation-alternative to surgical resection in selected cases[J]. Radiology, 2009, 251(2):599-604.
No related articles found!
阅读次数
全文


摘要