Research progress on risk factors and pathogenesis of osteoarthritis

doi:10.3877/cma.j.issn.1674-134X.2022.06.014

Abstract

Abstract:

Osteoarthritis is a joint degenerative disease due to multiple reasons, featured with the damage and abnormal metabolism of articular cartilage, subchondral bone or synovium and meniscus tissue. With the aging of population and the increase of obese people, the incidence of osteoarthritis is increasing year by year, leading to great social impact and economic burden. At present, its etiology remains unclear. This article summarized the risk factors and possible pathogenesis of osteoarthritis in order to introduce new insight for the prevention and treatment of osteoarthritis in the future.

Key words: Osteoarthritis, Risk factors

Xudong Wang, Ziji Zhang. Research progress on risk factors and pathogenesis of osteoarthritis[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2022, 16(06): 745-755.

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