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Chinese Journal of Joint Surgery(Electronic Edition) ›› 2018, Vol. 12 ›› Issue (06): 826-829. doi: 10.3877/cma.j.issn.1674-134X.2018.06.015

Special Issue:

• Review • Previous Articles     Next Articles

Research progress of chondrocyte autophagy in osteoarthritis

Haoran Hu1, Xuetao Xie1,(), Changqing Zhang1   

  1. 1. Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China
  • Received:2018-01-04 Online:2018-12-01 Published:2018-12-01
  • Contact: Xuetao Xie
  • About author:
    Corresponding author: Xie Xuetao, Email:

Abstract:

Objective

Osteoarthritis (OA), a common chronic degenerative disease inclinics, is the main cause of the disability and dysfunction of middle-aged and elderly people. Autophagy is not only essential to the maintenance of metabolic balance and renewal of cellular organs, but also has close relationship with the occurrence and development of OA.This article reviewed the latest research progress of chondrocyte autophagy in OA.

Key words: Osteoarthritis, Cartilage, Chondrocytes, Autophagy

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