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Chinese Journal of Joint Surgery(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (06): 720-727. doi: 10.3877/cma.j.issn.1674-134X.2025.06.011

• Review • Previous Articles    

Advances in research on platelet-rich plasma injection for partial-thickness rotator cuff tears

Junming Wei1,2, Dewei Xu1,2, Rongzhao Lin1,2, Liangquan Peng1,2,()   

  1. 1Shenzhen University, Shenzhen 518035, China
    2Sport Medicine of the Second People’s Hospital of Shenzhen, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China
  • Received:2025-02-24 Online:2025-12-01 Published:2026-01-22
  • Contact: Liangquan Peng

Abstract:

Rotator cuff tear is a common shoulder disease and one of the main causes of shoulder joint dysfunction and pain.Large epidemiological studies have identified a higher prevalence of rotator cuff tears in the general population.Rotator cuff tears can be divided into full tear and partial tear according to tear thickness.Partial rotator cuff tear is partial tears of rotator cuff thickness.Conservative treatment is usually preferred.Drug injection in conservative therapy is an important way to treat this kind of tendon disease.Among the most commonly used drug injections in clinic are corticosteroids,sodium hyaluronate and platelet-rich plasma(PRP).PRP is a platelet concentrate extracted from fresh whole blood after centrifugation.It is a commonly used biological agent at present.It has been widely used in clinical repair of various tissues and has achieved certain effects,especially in tendon diseases.However,the efficacy,safety and tear type of PRP in the treatment of partial rotator cuff tear remain to be explored. This review synthesized evidence from recent literature on PRP for partial-thickness rotator cuff tears (PTRCTs). It delineated the efficacy of PRP in pain and functional recovery, its safety profile, indications stratified by tear characteristics (location and grade), and its long-term benefits benchmarked against corticosteroids and other injectables. The analysis may provide critical insights to guide the rational clinical application of PRP.

Key words: Platelet-rich plasma, Rotator cuff tears, Injections, Intraarticular

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