To investigate the effect of platelet rich plasma in the treatment of talus cartilage injury.

According to the inclusion and exclusion criteria, 100 cases of adult unilateral talus cartilage injury in Weihaiwei people′s Hospital from January 2018 to January 2021 were included as the research objects. Inclusion criteria: unilateral talar cartilage injury was diagnosed; age 18 years ≤age <60 years; consciousness remained awake. Exclusion criteria: severe infection, autoimmune diseases, coagulation dysfunction, other orthopedic diseases, chronic basic diseases, mental disorders and cognitive impairment. The patients were randomly divided into control group and observation group according to random number table method. Arthroscopic ankle debridement was performed in the control group, while platelet-rich plasma was used in the observation group based on the control group. Serum inflammatory factors, complication rate, ankle range of motion, ankle score, ankle function score, pain score, comfort score and quality of life score were compared between the two groups, the incidence of complications was tested by chi square test, and the inflammatory factor index, ankle range of motion, ankle score, foot and ankle function score, pain score, comfort score and quality of life score were analyzed by t test.

After treatment, compared with the control group, the scores of interleukin-6, C-reactive protein, procalcitonin and pain in the observation group were lower (t=5.145, 5.621, 5.855 and 5.214, all P<0.01); the ankle plantar flexion, ankle back extension, ankle score, foot and ankle function score and comfort score in the observation group were higher (t=5.763, 6.099, 5.465, 6.115 and 5.918, all P<0.01). The scores of quality of life in the dimensions of physiology, psychology, environment and social relations in the observation group were higher (t=6.037, 6.277, 5.448 and 5.383, all P<0.01). The incidence of complications in the observation group was lower than that in the control group (χ²=4.396, P<0.05).

Arthroscopic ankle debridement combined with platelet-rich plasma treatment can effectively reduce the inflammatory reaction, reduce complications, improve ankle function and ankle range of motion, relieve pain and improve quality of life.