Progress of parathyroid hormone on bone and cartilage tissues

doi:10.3877/cma.j.issn.1674-134X.2021.02.013

Abstract

Abstract:

Parathyroid hormone (PTH) is one of the osteophilic endocrine hormones, which is involved in a variety of cellular biological processes. Previous studies have shown that PTH can inhibit the hypertrophic differentiation and apoptosis of chondrocytes and stimulate their proliferation, which has a moderate protection function on the cartilage cells by multiple signal pathways. In this paper, the mechanism of PTH in osteochondral tissue was reviewed.

Key words: Parathyroid hormone, Osteoblast, Osteoporosis, Cartilage, Mesenchymal stem cells

Yushu Chen, Huifeng Xie, Yanhong Zhang, Bo Bai, Yi Chen, Shujiang Zhang. Progress of parathyroid hormone on bone and cartilage tissues[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2021, 15(02): 214-218.

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