Research progress of anti-infective mechanism of platelets

doi:10.3877/cma.j.issn.1674-134X.2019.04.010

Abstract

Abstract:

Infection is one of the most common diseases, which can cause nonhealing wound, sepsis and other infectious diseases, then lead to multisystem organ failure and death. Platelets, one of the most common element of blood, is the first component which detect damage of endothelial cell and invasion of pathogen. In addition, platelets can internalize pathogens, secrete antimicrobial peptides, participate in and orchestrate the immune response. In this article, the research progress of anti-infective mechanism of platelets is reviewed.

Key words: Blood platelets, Infection, Immune system

Zhaoyuan Zhang, Fan Yang, Nianfang Lu, Ting Yuan, Changqing Zhang. Research progress of anti-infective mechanism of platelets[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2019, 13(04): 443-447.

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References 33

[1]	Yuan T, Zhang CQ, Tang MJ, et al. Autologous platelet-rich plasma enhances healing of chronic wounds[J]. Wounds, 2009, 21(10): 280-285.
[2]	Singh R, Dhayal RK, Sehgal PK, et al. To evaluate antimicrobial properties of platelet rich plasma and source of colonization in pressure ulcers in spinal injury patients[J]. Ulcers, 2015, (2015)1-7.
[3]	Delano MJ, Ward PA. Sepsis-induced immune dysfunction: can immune therapies reduce mortality？[J]. J Clin Invest, 2016, 126(1): 23-31.
[4]	Gotts Jeffrey E, Matthay Michael A. Sepsis: pathophysiology and clinical management[J/OL]. BMJ，2016，353:i1585. doi: 10.1136/bmj.i1585.
[5]	Claushuis TA, Van Vught LA, Scicluna BP, et al. Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients[J]. Blood, 2016, 127(24): 3062-3072.
[6]	Deppermann C, Kubes P. Platelets and infection[J]. Semin Immunol, 2016, 28(6): 536-545.
[7]	Klinger MH, Jelkmann W. Role of blood platelets in infection and inflammation[J]. J Interferon Cytokine Res. 2002, 22(9): 913-922.
[8]	Youssefian T, Drouin A, Masse JM, et al. Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation[J]. Blood, 2002, 99(11): 4021-4029.
[9]	Danon D, Jerushalmy Z, Devries A. Incorporation of influenze virus in human blood platelets invitro-electron microscopical observation[J]. Virology, 1959, 9(4): 719-722.
[10]	Hamzeh-Cognasse H, Damien P, Chabert AA, et al. Platelets and infections--complex interactions with bacteria[J/OL]. Front Immunol, 2015, 6: 82.doi: 10.3389/fimmu.2015.00082
[11]	Huang ZY, Chien P, Indik ZK, et al. Human platelet FcγRIIA and phagocytes in immune-complex clearance[J]. Mol Immunol, 2011, 48(4): 691-696.
[12]	Worth RG, Chien CD, Chien P, et al. Platelet FcγRIIA binds and internalizes IgG-containing complexes[J]. Exp Hematol, 2006, 34(11): 1490-1495.
[13]	Ali RA, Wuescher LM, Dona KR, et al. Platelets mediate host defense against staphylococcus aureus through direct bactericidal activity and by enhancing macrophage activities[J]. J Immunol, 2017, 198(1): 344-351.
[14]	Yeaman MR, Tang YQ, Shen AJ, et al. Purification and in vitro activities of rabbit platelet microbicidal proteins[J]. Infect Immun, 1997, 65(3): 1023-1031.
[15]	Clawson CC, White JG. Platelet interaction with bacteria.I.Reaction phases and effects of inhibitors[J]. Am J Pathol, 1971, 65(2): 367-380.
[16]	Ivanov IB, Gritsenko VA, Kuzmin MD. The effect of brief exposure to sub-therapeutic concentrations of chlorhexidine digluconate on the susceptibility of staphylococci to platelet microbicidal protein[J]. Surg Infect (Larchmt), 2015, 16(3):263-266.
[17]	Yeaman MR, Ibrahim AS, Jr JE, et al. Thrombin-induced rabbit platelet microbicidal protein is fungicidal in vitro[J]. Antimicrob Agents Chemother, 1993, 37(3): 546-553.
[18]	Tang YQ, Yeaman MR, Selsted ME. Antimicrobial peptides from human platelets[J]. Infect Immun, 2002, 70(12): 6524-6533.
[19]	Deuel TF, Senior RM, Huang JS. Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.[J]．J Clin Invest, 1982, 69(4): 1046-1049.
[20]	Miron RJ, Fujioka-Kobayashi M, Bishara M, et al. Platelet-rich fibrin and soft tissue wound healing: a systematic review[J]. Tissue Eng Part B Rev, 2017, 23(1): 83-99.
[21]	Anitua E, Aguirre JJ, Algorta J, et al. Effectiveness of autologous preparation rich in growth factors for the treatment of chronic cutaneous ulcers[J]. J Biomed Mater Res B Appl Biomater, 2008, 84B(2): 415-421.
[22]	Mariani E, Canella V, Berlingeri A, et al. Leukocyte presence does not increase microbicidal activity of Platelet-rich Plasma in vitro[J]. BMC Microbiol, 2015, 15(1): 149-161.
[23]	Deuel TF, Senior RM, Chang D, et al. Platelet factor 4 is chemotactic for neutrophils and monocytes[J]. Proc Natl Acad Sci USA, 1981, 78(7): 4584-4587.
[24]	Scheuerer B, Ernst M, Dürrbaum-Landmann I, et al. The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages[J]. Blood, 2000, 95(4): 1158-1166.
[25]	Criswell KA, Breider MA, Bleavins MR. EDTA-dependent platelet phagocytosis acytochemical, ultrastructural，and functional characterization[J]. Am J Clin Pathol, 2001, 115(3): 376-384.
[26]	李海鹏，姚建华．中性粒细胞在炎症反应中的作用及机制[J]．医学综述，2015，21(9):1576-1578.
[27]	Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors[J]. Nat Immunol, 2010, 11(5): 373-384.
[28]	Garraud O, Cognasse F. Are platelets cells？And if yes，are they immune cells？[J/OL]．Front Immunol，6:70. doi：10.3389/fimmu.2015.00070.
[29]	Cognasse F, Hameh-Cognasse H, Lafarge SA, et al. Human platelets can activate peripheral blood B cells and increase production of immunoglobulins[J]. Exp Hematol, 2007, 35(9): 1376-1387.
[30]	Peerschke EI, Yin W, Ghebrehiwet B. Complement activation on platelets：implications for vascular inflammation and thrombosis[J]. Mol Immunol, 2010, 47(13, SI): 2170-2175.
[31]	Blair P, Flaumenhaft R. Platelet alpha-granules：basic biology and clinical correlates[J]. Blood Rev, 2009, 23(4): 177-189.
[32]	Semple JW, Italiano J, Freedman J. Platelets and the immune continuum[J]. Nat Rev Immunol, 2011, 11(4): 264-274.
[33]	李明，章军辉，李淑敏，等．应用自体富血小板血浆治疗慢性难愈性创面的实验研究[J/CD]．中华关节外科杂志(电子版)，2016，10(6):624-629.

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