Meta analysis on re-infection following one and two stage revisions of infected total hip arthroplasty

doi:10.3877/cma.j.issn.1674-134X.2019.01.014

Abstract

Abstract:

Objective

To compare the re-infection of infected total hip arthroplasty (THA) treated by one stage revision and two sate revision.

Methods

The papers about THA treated by one stage and two stage revision were searched on Pubmed、Medline and EMBase data(January, 1988 to Jananuary, 2017). The papers were selected according to the criteria(the papers about THA treated by one stage and two stage revisions, excluding treated by single treatment). The re-infection rate was analysed by meta-analysis. Review Manger 5.3 was used for data analysis.

Results

Ten articles were collected from 1 084 articles finally. 1 116 cases infected THA were studied, which 480 cases were treated by one-stage revision and 636 cases were treated by two-stage revision. Re-infection rate between the two group results shows[OR=1.40, 95%CI(0.92, 2.15), P =0.12]. If the soft tissue was healthy、the bone defect was small and the pathogen was determined, the re-infection rates were similar between one stage and two stage revisions[OR=0.44, 95%CI(0.13, 1.41), P =0.17]; If the soft tissue、bone defects and pathogens were not considered, the difference in the re-infection rate was statistically significant [OR=1.79, 95%CI(1.11, 2.88), P=0.02].

Conclusion

In the treatment of the infected total hip arthroplasty, the local condition may influence the re-infection rate of one-stage and two stage revision surgery.

Key words: Arthroplasty, replacement, hip, Reoperation, Infection, Meta-analysis

Lineng Lin, Hui Wang, Xiaotang Sun, Zhihong Zhang, Wanming Wang. Meta analysis on re-infection following one and two stage revisions of infected total hip arthroplasty[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2019, 13(01): 73-77.

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Figures/Tables 3

References 26

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序号	作者	年份	期刊	类型	病例数	一期和二期翻修是否有选择依据
1	Born^[12]	2016	Acta Orthopaedica	回顾性	81	是
2	Choi^[13]	2013	The Journal of Arthroplasty	回顾性	51	否
3	De Man^[14]	2011	Acta Orthopaedica	回顾性	72	是
4	Engesater^[15]	2011	Acta Orthopaedica	回顾性	477	否
5	Giulieri^[16]	2004	Infection	回顾性	47	是
6	Hope^[17]	1989	Journal of Bone & Joint Surgery	回顾性	91	否
7	Klouche^[18]	2012	Orthopaedics & Traumatology Surgery & Research	回顾性	84	是
8	Morscher^[19]	1990	International orthopaedics	回顾性	74	否
9	Oussedik^[20]	2010	The Journal of bone and joint surgery	回顾性	50	是
10	Wolf^[21]	2014	International Orthopaedics	回顾性	92	否

序号	作者	年份	期刊	类型	病例数	一期和二期翻修是否有选择依据
1	Born^[12]	2016	Acta Orthopaedica	回顾性	81	是
2	Choi^[13]	2013	The Journal of Arthroplasty	回顾性	51	否
3	De Man^[14]	2011	Acta Orthopaedica	回顾性	72	是
4	Engesater^[15]	2011	Acta Orthopaedica	回顾性	477	否
5	Giulieri^[16]	2004	Infection	回顾性	47	是
6	Hope^[17]	1989	Journal of Bone & Joint Surgery	回顾性	91	否
7	Klouche^[18]	2012	Orthopaedics & Traumatology Surgery & Research	回顾性	84	是
8	Morscher^[19]	1990	International orthopaedics	回顾性	74	否
9	Oussedik^[20]	2010	The Journal of bone and joint surgery	回顾性	50	是
10	Wolf^[21]	2014	International Orthopaedics	回顾性	92	否

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