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中华关节外科杂志(电子版) ›› 2026, Vol. 20 ›› Issue (02) : 194 -205. doi: 10.3877/cma.j.issn.1674-134X.2026.02.008

临床论著

6自由度步态床旁预测老年患者跌倒风险的应用
冼明桦1,2, 刘华章4, 欧阳兰飞3, 谢珍艳2,5, 钟国庆2,5, 林金鹏2,5, 黄星3, 黄帅4, 谢可乐2,5, 曾东禹2,5, 黄文汉2,5, 李丽萍1, 王旭平3, 梁会营4, 张余1,2,5,()   
  1. 1 515041 汕头大学公共卫生学院
    2 510080 广州,南方医科大学附属广东省人民医院(广东省医学科学院)骨肿瘤科
    3 210046 南京,泰康仙林鼓楼医院耳鼻喉头颈外科
    4 510080 广州,南方医科大学附属广东省人民医院(广东省医学科学院)医学大数据中心
    5 510080 广州,广东省骨缺损功能修复与生物材料工程技术研究中心
  • 收稿日期:2025-10-29 出版日期:2026-04-01
  • 通信作者: 张余
  • 基金资助:
    广州市重点研发计划(2023B01J0022); 广东省重点领域研发计划(2024B0101080001); 泰康仙林鼓楼医院院内重点项目(TKKYZD20240802); 南京市卫生科技发展专项资金资助项目(ZDXX25213)

Translating gait biomechanics into bedside fall risk prediction for hospitalized older adults

Minghua Xian1,2, Huazhang Liu4, Lanfei Ouyang3, Zhenyan Xie2,5, Guoqing Zhong2,5, Jinpeng Lin2,5, Xing Huang3, Shuai Huang4, Kele Xie2,5, Dongyu Zeng2,5, Wenhan Huang2,5, Liping Li1, Xuping Wang3, Huiying Liang4, Yu Zhang1,2,5,()   

  1. 1 School of Public Health, Shantou University, Shantou 515041, China
    2 Department of Orthopedic Oncology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China
    3 Department of Otorhinolaryngology and Head and Neck Surgery, Taikang Xianlin Gulou Hospital, Nanjing 210046, China
    4 Medical Big Data Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China
    5 Guangdong Engineering Technology Research Center of functional repair of bone defects and biomaterials, Guangzhou 510080, China
  • Received:2025-10-29 Published:2026-04-01
  • Corresponding author: Yu Zhang
引用本文:

冼明桦, 刘华章, 欧阳兰飞, 谢珍艳, 钟国庆, 林金鹏, 黄星, 黄帅, 谢可乐, 曾东禹, 黄文汉, 李丽萍, 王旭平, 梁会营, 张余. 6自由度步态床旁预测老年患者跌倒风险的应用[J/OL]. 中华关节外科杂志(电子版), 2026, 20(02): 194-205.

Minghua Xian, Huazhang Liu, Lanfei Ouyang, Zhenyan Xie, Guoqing Zhong, Jinpeng Lin, Xing Huang, Shuai Huang, Kele Xie, Dongyu Zeng, Wenhan Huang, Liping Li, Xuping Wang, Huiying Liang, Yu Zhang. Translating gait biomechanics into bedside fall risk prediction for hospitalized older adults[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2026, 20(02): 194-205.

目的

探讨基于下肢6自由度(6DOF)步态运动学特征的深度学习模型在老年住院患者跌倒风险床旁预测中的应用价值。

方法

采用横断面研究设计,于广东省人民医院骨科病区纳入207例老年住院患者(年龄65~93岁)。纳入标准为:年龄≥60岁、意识清楚且能独立行走≥10 m;排除严重创伤或急性并发症无法完成测试者。采集受试者下肢6DOF步态运动学数据,并依据Morse跌倒量表(MFS)评分将受试者分为低风险、中风险及高风险组。将步态时序数据转化为二维步态图像后输入注意力增强的一维卷积神经网络(1D-CNN)模型进行训练与分类,二维步态图仅用于模型可视化展示。模型性能通过准确率(accuracy)、精确率(precision)、召回率(recall)及F1得分进行评估,并通过受试者工作特征曲线(ROC)及混淆矩阵进行分析。

结果

本研究共纳入207例患者,其中高风险59例、中风险72例、低风险76例。模型在独立测试集(n=41)上的分类准确率为0.878,精确率为0.874,召回率为0.897,F1值为0.882。高风险组召回率为1.000,未出现高危跌倒个体漏检。ROC曲线分析显示该模型在不同风险等级上均具有良好的区分能力。

结论

基于6DOF步态运动学特征构建的注意力增强1D-CNN模型可有效实现老年住院患者跌倒风险分层,并具有较高的预测准确性与临床可解释性,可为病房环境下的床旁跌倒风险筛查提供客观评估工具。

Objective

To investigate the clinical application of a deep-learning model based on six-degree-of-freedom (6DOF) lower-limb gait kinematics for bedside prediction of fall risk in hospitalized older adults.

Methods

This cross-sectional study enrolled 207 hospitalized older adults (65 to 93 years) from the orthopedic wards of Guangdong Provincial People’s Hospital. Inclusion criteria: age≥60 years, clear consciousness, and the ability to walk independently for at least 10 m. Patients unable to complete gait testing due to severe trauma or acute complications were excluded. Lower-limb 6DOF gait kinematic data were collected using a motion-capture system. According to the Morse fall scale (MFS), participants were categorized into low-, medium-, and high-risk groups. Gait time-series data were transformed into two-dimensional gait maps and analyzed using an attention-enhanced one-dimensional convolutional neural network (1D-CNN). Model performance was evaluated using accuracy, precision, recall, and F1 score, and further assessed with receiver operating characteristic (ROC) curves and confusion matrix analysis.

Results

A total of 207 participants were included, comprising 59 high-risk, 72 medium-risk, and 76 low-risk individuals. On the independent test set (n=41), the model achieved an accuracy of 0.878, precision of 0.874, recall of 0.897, and an F1 score of 0.882. The recall for the high-risk group reached 1.000, indicating no missed high-risk fallers. ROC analysis demonstrated good discriminative ability across different risk levels.

Conclusions

The attention-enhanced 1D-CNN model based on 6DOF gait kinematics can effectively stratify fall risk in hospitalized older adults with high predictive performance and clinical interpretability. This approach provides an objective bedside tool for fall-risk screening in hospital settings.

表1 入口统计学与人体测量特征组间比较
Table 1 Comparisons of demographic and anthropometric characteristics among groups
图1 受试者疾病类型分布
Figure 1 Distribution of disease types among participants
图2 预测模型构建过程
Figure 2 Workflow of model development
图3 模型内部结构
Figure 3 Structure of model
表2 模型的分类及评价
Table 2 Model classification andassessment
表3 模型方法的比较
Table 3 Comparisons on models
图4 模型训练与验证期间的损失与准确率变化趋势 注:图中曲线包括训练集损失值(loss)、验证集损失值(val_loss)、训练集准确率(acc)和验证集准确率(val_acc);X轴为训练轮次,Y轴为对应的损失值或准确率
Figure 4 The trend of loss and accuracy changes during model training and validation Note: the curves in the figure are training set loss value (loss), validation set loss value (val_loss), training set accuracy (acc), and validation set accuracy (val_cc); X-axis represents the training epochs, while Y-axis represents the corresponding loss value or accuracy
图5 模型在测试集上的混淆矩阵 注:矩阵的行代表真实类别,列代表模型预测类别;矩阵中的数值表示样本数量
Figure 5 The confusion matrix of the model on the test set Note: the rows of the matrix represent the true class, and the columns represent the predicted class of the model; the values in the matrix represent the number of samples
图6 Model DC(本模型)与其他基线模型在测试集上的ROC(受试者工作特征曲线) 注:X轴为假阳性率(1-特异度),Y轴为真阳性率(灵敏度)
Figure 6 ROC (receiver operating characteristic curves) of model DC and other baseline models on the test set Note: X-axis represents the false positive rate (1-specificity), while the Y-axis represents the trueoositive rate (sensitivity)
图7 模型的特征可视化结果。图A为DOF1(内收/外展自由度)的特征热图;图B为DOF3(屈曲/伸展自由度)的特征热图 注:每个子图上半部分为原始步态信号,下半部分由注意力热图(红色条带)和提取特征(蓝色曲线)构成,红色条带的深浅反映了该时间步特征对模型分类的重要性
Figure 7 Visualization of model features. A is the characteristic heat map of DOF1 (inward/outward degrees of freedom); B is the characteristic heat map of DOF3 (degree of freedom in flexion/extension) Note: the upper half of each subgraph is the original gait signal, while the lower half consists of an attention heatmap (red stripe) and extracted features (blue curve), the depth of the red stripe reflects the importance of the time step feature for model classification
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