切换至 "中华医学电子期刊资源库"

中华关节外科杂志(电子版) ›› 2026, Vol. 20 ›› Issue (01) : 15 -16. doi: 10.3877/cma.j.issn.1674-134X.2026.01.002

专家述评

膝骨关节炎全周期精准诊疗新范式
童培建1, 赵雪飞2, 夏汉庭1,2, 张扬1,3, 庄新凯2   
  1. 1浙江中医药大学附属第一医院(浙江省中医院)
    2浙江中医药大学第一临床医学院
    3浙江中医药大学药学院
  • 收稿日期:2025-01-02 出版日期:2026-02-01

New paradigm for full cycle precise diagnosis and treatment of knee osteoarthritis

Peijian Tong, Xuefei Zhao, Hanting Xia   

  • Received:2025-01-02 Published:2026-02-01
引用本文:

童培建, 赵雪飞, 夏汉庭, 张扬, 庄新凯. 膝骨关节炎全周期精准诊疗新范式[J/OL]. 中华关节外科杂志(电子版), 2026, 20(01): 15-16.

Peijian Tong, Xuefei Zhao, Hanting Xia. New paradigm for full cycle precise diagnosis and treatment of knee osteoarthritis[J/OL]. Chinese Journal of Joint Surgery(Electronic Edition), 2026, 20(01): 15-16.

[1]
Dang Y, Liu Y, Zhang B, et al. Aging microenvironment in osteoarthritis focusing on early-stage alterations and targeted therapies[J/OL]. Bone Res, 2025, 13(1): 84. DOI:10.1038/s41413-025-00465-6.
[2]
Lou P, Lu X, Li M, et al. Single-cell sequencing reveals a senescent immune landscape in bone marrow lesions inducing articular cartilage damage in osteoarthritis[J/OL]. Bone Res, 2025, 13(1): 94. DOI:10.1038/s41413-025-00467-4.
[3]
Long Z, Zhang M, Zhang T, et al. The effectiveness and safety of mesenchymal stem cells in the treatment of osteoarthritis: a systematic review and meta-analysis of 28 randomized controlled trials[J/OL]. Stem Cells Int, 2022, 2022: 6151866.DOI:10.1155/2022/6151866.
[4]
Mushenkova NV, Nikiforov NG, Shakhpazyan NK, et al. Phenotype diversity of macrophages in osteoarthritis: implications for development of macrophage modulating therapies[J/OL]. Int J Mol Sci, 2022, 23(15): 8381. DOI:10.3390/ijms23158381.
[5]
Sokolove J, Lepus CM. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations[J]. Ther Adv Musculoskelet Dis, 2013, 5(2): 77-94.
[6]
Thomson A, Hilkens CMU. Synovial macrophages in osteoarthritis: the key to understanding pathogenesis?[J/OL]. Front Immunol, 2021, 12: 678757.DOI:10.3389/fimmu.2021.678757.
[7]
Chu CR, Williams AA, Coyle CH, et al. Early diagnosis to enable early treatment of pre-osteoarthritis[J/OL]. Arthritis Res Ther, 2012, 14(3): 212. DOI:10.1186/ar3845.
[8]
Im G-I. The concept of early osteoarthritis and its significance in regenerative medicine[J]. Tissue Eng Regen Med, 2022, 19(3): 431-436.
[9]
Macri EM, Neogi T, Jarraya M, et al. Magnetic resonance imaging-defined osteoarthritis features and anterior knee pain in individuals with, or at risk for, knee osteoarthritis: a multicenter study on osteoarthritis[J]. Arthritis Care Res, 2022, 74(9): 1533-1540.
[10]
Nasser Y, Jennane R, Chetouani A, et al. Discriminative regularized auto-encoder for early detection of knee osteoarthritis: data from the osteoarthritis initiative[J]. IEEE Trans Med Imaging, 2020, 39(9): 2976-2984.
[11]
Gai X, Cai H, Wang J, et al. Construction of multi-scale feature fusion segmentation model of MRI knee images based on dual attention mechanism weighted aggregation[J]. Technol Health Care, 2024, 32(S1): 277-286.
[12]
Zheng H, Chen C. Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies[J/OL]. BMJ Open, 2015, 5(12): e007568. DOI:10.1136/bmjopen-2014-007568.
[13]
Han X, Liao R, Li X, et al. Mesenchymal stem cells in treating human diseases: molecular mechanisms and clinical studies[J/OL]. Signal Transduct Target Ther, 2025, 10(1): 262. DOI:10.1038/s41392-025-02313-9.
[14]
Han Y, Yang J, Fang J, et al. The secretion profile of mesenchymal stem cells and potential applications in treating human diseases[J/OL]. Signal Transduct Target Ther, 2022, 7(1): 92. DOI:10.1038/s41392-022-00932-0.
No related articles found!
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?