切换至 "中华医学电子期刊资源库"

中华关节外科杂志(电子版) ›› 2018, Vol. 12 ›› Issue (01) : 107 -110. doi: 10.3877/cma.j.issn.1674-134X.2018.01.019

所属专题: 文献

个案报道

儿童股骨头坏死病的1个家系调查
颜登鲁1,(), 廖静娴2, 张在恒3, 朱豪东4   
  1. 1. 541001 桂林医学院附属医院骨外科;518182 深圳市南山区人民医院骨外科
    2. 518182 深圳市南山区人民医院骨外科
    3. 518101 深圳市宝安区人民医院骨外科
    4. 511400 广州市南沙区人民医院骨外科
  • 收稿日期:2016-01-20 出版日期:2018-02-01
  • 通信作者: 颜登鲁
  • 基金资助:
    广东省科技厅科技计划项目(2014A020212041); 深圳市科创委科技计划项目(JCYJ20140411091151442)

Family investigation on femoral head necrosis in child

Denglu Yan1(), Jingxian Liao2, Zaiheng Zhang3   

  • Received:2016-01-20 Published:2018-02-01
  • Corresponding author: Denglu Yan
引用本文:

颜登鲁, 廖静娴, 张在恒, 朱豪东. 儿童股骨头坏死病的1个家系调查[J]. 中华关节外科杂志(电子版), 2018, 12(01): 107-110.

Denglu Yan, Jingxian Liao, Zaiheng Zhang. Family investigation on femoral head necrosis in child[J]. Chinese Journal of Joint Surgery(Electronic Edition), 2018, 12(01): 107-110.

图1 Perthes病家系遗传模式图。其中Ⅰ代和Ⅱ代均已经去世,VI代中?代表该儿童年龄小于13岁且目前未确诊为Perthes病,或者由于家长原因不愿意接受X线检查。Ⅲ代中?代表该成员有症状,但是由于个人原因拒绝形X线检查
图4 Ⅲ 7骨盆X线正位片。先症者的姐姐,女性53岁,示双侧股骨头坏死(发病年龄6岁)
图7 Ⅳ 12骨盆X线正位片。先症者的姐姐(Ⅲ 7)的儿子,男性29岁,示双侧股骨头坏死(发病年龄5岁)
图10 Ⅲ 11骨盆X线正位片。先症者的表姐,女性57岁,示双侧股骨头坏死(发病年龄6岁)
图13 Ⅲ 5骨盆X线正位片。先症者的表姐Ⅲ 5,女性58岁,示双侧股骨头坏死(发病年龄6岁)
图16 Ⅳ 7骨盆X线正位片。先症者的表姐Ⅲ 5的小儿子,男性31岁,示双侧股骨头坏死(发病年龄和4岁)
图17 Ⅴ 4骨盆X线正位片。先症者的表姐Ⅲ 5的外孙女(Ⅳ 3的女儿),女性13岁,双髋疼痛5年,示双侧股骨头变性坏死不明显(发病年龄8岁)
[1]
Catterall A. The place of valgus extension femoral osteotomy in the late management of children with Perthes′ disease[J]. Ortop Traumatol Rehabil, 2007, 6(6): 764-769.
[2]
Shah H. Perthes disease: evaluation and management[J]. Orthop Clin North Am, 2014, 45(1): 87-97.
[3]
Yang J,Yü ZT,Zhang JL, et al. Prognostic factors and outcomes of Legg-Calve-Perthes disease[J]. Zhonghua Yi Xue Za Zhi, 2013, 93(21):1640-1643.
[4]
Karol LA. Legg-Calve-Perthes disease 100 years on: what have we learned?[J]. J Am Acad Orthop Surg, 2010, 18(11):643-644.
[5]
Woratanarat P,Thaveeratitharm C,Woratanarat T, et al. Meta-analysis of hypercoagulability genetic polymorphisms in Perthes disease[J]. J Orthop Res, 2014, 32(1): 1-7.
[6]
Miyamoto Y,Matsuda T,Kitoh H, et al. A recurrent mutation in type II collagen gene causes Legg-Calve-Perthes disease in a Japanese family[J]. Hum Genet, 2007, 121(5): 625-629.
[7]
Westhoff B,Krauspe R,Kalke AE, et al. Urinary excretion of deoxypyridinoline in Perthes′ disease: a prospective, controlled comparative study in 83 children[J]. J Bone Joint Surg Br, 2006, 88(7): 967-971.
[8]
Al-Omran AK,Sadat-Ali M. Legg-Calve-Perthes disease in two generations of male family members: a case report[J]. J Orthop Surg (Hong Kong), 2013, 21(2): 258-261.
[9]
Starr-Moss AN,Nowend KL,Alling KM, et al. Exclusion of COL2A1 in canine Legg-Calve-Perthes disease[J]. Anim Genet, 2012, 43(1): 112-113.
[10]
Terjesen T,Wiig O,Svenningsen S. The natural history of Perthes′ disease[J]. Acta Orthop, 2010, 81(6): 708-714.
[11]
Frias Austria R. Legg-Calve-Perthes disease[J]. Acta Ortop Bras, 2009, 23(3):172-181
[12]
Johannesen J,Briody J,Mcquade M, et al. Systemic effects of zoledronic acid in children with traumatic femoral head avascular necrosis and Legg-Calve-Perthes disease[J]. Bone, 2009, 45(5): 898-902.
[13]
Glueck CJ,Glueck HI,Greenfield D, et al. Protein C and S deficiency, thrombophilia, and hypofibrinolysis: pathophysiologic causes of Legg-Perthes disease[J]. Pediatr Res, 1994, 35(4 Pt 1): 383-388.
[14]
Balasa VV,Gruppo RA,Glueck CJ, et al. Legg-Calve-Perthes disease and thrombophilia[J]. J Bone Joint Surg Am, 2004, 86-A(12): 2642-2647.
[15]
Mumme T,Berkemeier E,Maus U, et al. Coxitis fugax--the beginning of Perthes′ disease?[J]. Z Orthop Unfallchir, 2005, 143(5):529-533.
[16]
Neidel J,Zander D,Hackenbroch MH. Low plasma levels of insulin-like growth factor I in Perthes′ disease. A controlled study of 59 consecutive children[J]. Acta Orthop Scand, 1992, 63(4):393-398.
[17]
Neidel J,Boddenberg B,Zander D, et al. Thyroid function in Legg-Calve-Perthes disease:cross-sectional and longitudinal study[J]. J Pediatr Orthop, 1993, 13(5): 592-597.
[18]
Neidel J,Schonau E,Zander D, et al. Hackenbroch MH: Normal plasma levels of IGF binding protein in Perthes′ disease. Follow-up of previous report[J]. Acta Orthop Scand, 1993, 64(5):540-542.
No related articles found!
阅读次数
全文


摘要