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Chinese Journal of Joint Surgery(Electronic Edition) ›› 2026, Vol. 20 ›› Issue (02): 164-173. doi: 10.3877/cma.j.issn.1674-134X.2026.02.005

• CLINICAL RESEARCHES • Previous Articles    

Association of preoperative hip muscle quality with functional outcomes after total hip arthroplasty

Zhengyuan Bao1, Hung-Kang Tsai1, Can Cui2, Wing-Hoi Cheung2, Qing Jiang1, Zhihong Xu1,()   

  1. 1 Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
    2 Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China
  • Received:2025-11-23 Online:2026-04-01 Published:2026-05-29
  • Contact: Zhihong Xu

Abstract:

Objective

To identify preoperative muscle compositions of operated and contralateral sides and examine the association with postoperative walking and chair-raising outcomes after unilateral total hip arthroplasty (THA).

Methods

This retrospective study included 305 patients who underwent unilateral primary THA due to femoral head necrosis or hip osteoarthritis from January 2022 to December 2023. Exclusion criteria were: a history of long-term bedridden, prior hip surgery history on the operative side, hip dysplasia, severe complications after THA, incomplete imaging or functional data. A total of 133 patients were included in this study. Bilateral total muscle area index (TMI), normal attenuation muscle area index (NAMI) and fat infiltration (FI) of hip muscles were examined on a preoperative axial CT image. Six-meter walking test (6mWT) and five times sit-to-stand test (5-STST) were conducted at three-month follow-up. Paired t test or Wilcoxon rank sum test were used to compare the differences between bilateral muscle compositions. Pearson correlation coefficients were calculated to determine the factors associated with 6mWT and 5-STST results. Factors with P<0.1 in the univariate analysis were included in multivariate linear regression analysis.

Results

Preoperatively, TMI was significantly higher on the contralateral side of gluteus maximus (t=-10.700, P<0.001), gluteus medius (Z=-3.407, P=0.001), iliopsoas (t=-6.839, P<0.001), and rectus femoris (t=-6.327, P<0.001) compared with the operative side. In terms of muscle quality, NAMI was significantly higher and FI was significantly lower on the contralateral side of gluteus maximus (NAMI: t=-12.359, P<0.001, FI: Z=-8.774, P<0.001), gluteus medius (NAMI: t=-8.213, P<0.001, FI: Z=-8.241, P<0.001), gluteus minimus (NAMI: t=-5.110, P<0.001, FI: Z=-7.063, P<0.001), iliopsoas (NAMI: t=-9.010, P<0.001, FI: Z=-7.587, P<0.001), piriformis (NAMI: Z=-5.841, P<0.001, FI: Z=-6.569, P<0.001), and rectus femoris (NAMI: t=-6.835, P<0.001, FI: Z=-4.500, P<0.001) compared with the operative side. In multivariate regression analysis, age (B=0.123, P<0.001) and contralateral gluteus minimus FI (B=5.948, P=0.013) were independently positively associated with 5-STST time. Contralateral gluteus maximus TMI (B=-0.438, P=0.001) was independently negatively associated with 5-STST time. Age (B=-0.006, P<0.001) and contralateral iliopsoas FI (B=-1.178, P<0.001) were independently negatively associated with 6mWT speed. Contralateral gluteus minimus TMI (B=0.047, P=0.025) was independently positively associated with 6mWT speed.

Conclusion

The preoperative muscle qualities of gluteus maximus, gluteus minimus and iliopsoas on the non-operative side were significantly associated with postoperative gait and sit-to-stand abilities at the three-month follow-up.

Key words: Hip joint, Muscular atrophy, Arthroplasty, replacement, hip, Rehabilitation

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