To analyze the impact of a perioperative blood management program based on multidisciplinary collaboration on blood loss and blood transfusion rate during total knee arthroplasty (TKA).

Patients who underwent TKA in the First Affiliated Hospital of Harbin Medical University from March 2022 to February 2024 were selected. After the inclusion criteria (primary TKA for end-stage knee disease, preoperative hemoglobin≤100 g/L, normal coagulation function) and exclusion criteria (bilateral TKA, tranexamic acid allergy or contraindication, high risk or history of thrombosis, severe cardiovascular and cerebrovascular diseases) screening, 86 patients were finally enrolled the study. According to the random number table method, the participants were divided into the control group (given routine blood management scheme) and the observation group (perioperative blood management scheme based on multidisciplinary collaboration), with 43 cases in each group. T test, chi square test and other statistical methods were used to analyze and compare the intraoperative blood loss, blood transfusion rate, operation time, hemoglobin (Hb) and complications between the two groups, as well as the satisfaction of the two groups.

The intraoperative blood loss and perioperative blood transfusion volume in the observation group were less than those in the control group, the blood transfusion rate was lower than that in the control group, and the operation time was shorter than that in the control group (t=6.197, 12.742, 5.988, χ²=4.440), and the differences were statistically significant (all P<0.05). On the third day after the operation, Hb levels of both groups decreased compared with those before the operation, while Hb level of the observation group was higher than that of the control group, and the difference was statistically significant (t=3.339, P< 0.05). The total incidence of complications in the observation group was lower than that in the control group, the average length of hospital stay was shorter than that in the control group, and the patient satisfaction score was higher than that in the control group (χ²=4.440, t=2.917, 5.747), and the differences between the two groups were statistically significant (all P<0.05).

The multidisciplinary blood management program, through precise hemostasis techniques, dynamic monitoring and precise execution by the nursing team, and anemia pretreatment, can reduce blood loss and blood transfusion requirements in patients with total knee arthroplasty (TKA). Nursing plays a crucial role in carrying out medical orders, warning of complications and promoting early rehabilitation, thereby accelerating the rehabilitation process and enhancing patient satisfaction.